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Schizophrenia & Psychosis - Organisations

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Aido
Aido

Aido is digitalising the evidence based treatment of Schizophrenia. The Aido service consists of a mobile application and a smart pill box that together ensure that the medicines are taken on time. In addition the application tracks the overall level of the disease. By improving the adherence to the treatment, the patient's symptoms remain low, the ability to function increases and the quality of life improves. In addition, better adherence reduces the risk of a relapse significantly. Aido's application features include:

  • Reminding the patient to take the pills
  • Tracking how the pills have been taken
  • Tracking the mood and other symptoms
  • Sleep and social activity monitoring
  • Simple user interface
  • All platforms: IOS and Android

Aido Healthcare is a Finnish company, founded in 2016, aiming to digitalise and improve the evidence based treatment of schizophrenia and psychosis patients. Aido's mission is to escort the mentally unwell towards independent life, to a more controlled and balanced living, and full participation in society. We want to increase the peace in families affected by mental illness, and to strengthen the sense of security in the community. We help the health professionals to achieve better results, and the society to attain considerable savings and reallocation of resources for effective care. Aido's vision is to be a leading eHealth company whose smart and easy-to-use digital services help the patient to adhere to treatment, and professionals to monitor the effectiveness of care; improving the quality of life of the patient and his/her close ones, making sure that care is appropriate, and attaining considerable savings for the society.

 

For Patient

The Aido service consists of a mobile application and a smart pill box that together ensure that the medicines are taken on time. In addition the application tracks the overall level of the disease. By improving the adherence to the treatment, the patient's symptoms remain low, the ability to function increases and the quality of life improves. In addition, better adherence reduces the risk of a relapse significantly.

 

For Healthcare Professionals

With a real-time dashboard and information channel, healthcare professionals are able to react immediately to the discontinuation
of outpatient’s medication or to the adherence to the treatment. The dashboard is also a tool that a healthcare professional can use to interact with the patient psycho-educationally. This will provide the patient with the information they need about the effects of drug treatment on
health and condition.

For Society

Aido enhances the specialty care of schizophrenia and other psychotic diseases by strengthening the patient's  adherence to the treatment. This reduces the risk of disease recurrence and saves costs. Effects also appear in the patient care, for example in improved performance and quality of life.

 

Organisation

Country: Finland

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All Signal
All Signal

All Signal is a blog where Monica Cassani publishes a range of posts about mental health. Monica is the main author and editor of Everything Matters: Beyond Meds which is mostly an archive now. Monica is working on organizing her current thoughts and mostly post bits and pieces these days. 

 

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Country: United Kingdom of Great Britain and Northern Ireland

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Beyond Meds
Beyond Meds

Beyond Meds is a website that documents and shares many natural methods of self-care for finding and sustaining health in body, mind and spirit. This blog also deals with wider issues in the socio/political and spiritual realms as they pertain to mental health and human rights issues surrounding psychiatry. The blog and the content has evolved over time. The archives reflect that. The author saw the system from both sides – as a social worker and as a person whose life was severely ruptured by psychiatric drugs. She writes critically about the system, as well as about holistic pathways of healing without medication.  Everything Matters documents and shares many natural methods of self-care for finding and sustaining health in body, mind and spirit.

 

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Campaign for the Abolition of Schizophrenia
Campaign for the Abolition of Schizophrenia

 

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Clinical Schizophrenia & Related Psychoses
Clinical Schizophrenia & Related Psychoses

Clinical Schizophrenia & Related Psychoses (CS) is a peer-reviewed quarterly publication that aims to provide psychiatrists and other healthcare professionals with the latest research and advances in the diagnosis and treatment of schizophrenia and related psychoses. CS is a practice-oriented publication focused exclusively on the newest research findings, guidelines, treatment protocols, and clinical trials relevant to patient care. It aims to present peer-reviewed original research and analysis that deals exclusively with the treatment of schizophrenia and related psychoses and is directly relevant to patient care through:

  • Unique, disease-specific focus dedicated entirely to the latest research and advances in the diagnosis and treatment of schizophrenia and related psychoses.
  • Clinically-driven content that provides practice-oriented original research results, case reports, comprehensive reviews, current treatment protocols, drug therapy updates, and clinical trial news, as well as meeting highlights from major conferences.
  • Peer-reviewed credibility.
  • Exceptional 20/80 ad-to-edit ratio - delivers maximum editorial coverage for our readers and maximum exposure for our select sponsors.

Clinical Schizophrenia & Related Psychoses (CS) is a peer-reviewed quarterly journal providing psychiatrists and other physicians and healthcare professionals with clinical information relevant to the diagnosis and treatment of people suffering from schizophrenia and other severe mental illnesses. CS is a practice-oriented publication covering the latest research, clinical trials, case reports, and treatment advances relevant to the complete treatment of people suffering from schizophrenia and other severe mental illnesses. Their distinguished Editorial Board is comprised of prominent schizophrenia researchers and clinicians from around the world

 

Organisation

Address: P.O. Box 193 Montvale, NJ 07645

Country: United States of America

Email: peter.buckley@vcuhealth.org

Call 201-391-8411

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Hearing Voices: Suffering, Inspiration & The Everyday
Hearing Voices: Suffering, Inspiration & The Everyday

Hearing Voices is the online version of Hearing Voices: suffering, inspiration and the everyday. This is the world’s first exhibition to explore voice-hearing from personal, scientific, cultural, literary and theological perspectives.  The exhibition is the result of a collaboration between Durham University’s Palace Green Library and Hearing the Voice. It was produced in close partnership with voice-hearers, their families and allies, who were involved in the project as contributing artists, co-curators and advisors. The website contains:

  • Images of the key displays
  • Podcasts
  • Interactive presentations and
  • Useful resources for anyone with an interest in hearing voices and other unusual experiences. 

They are currently touring adapted versions of Literary Voices, Communities and Collectives and the Listen Up! artworks to a range of national and international settings including conferences, community centres, clinical contexts and festivals. If you would like to make a suggestion for a suitable venue, please get in touch with us to discuss the details. You can join in the conversation around the exhibition on social media with the hashtag #HearingVoicesDU.

Communities & Collectives
Communities & Collectives

Communities and Collectives is a section of the exhibition co-curated with Paul Baker, social media co-ordinator for Intervoice.

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Everyday Voices
Everyday Voices

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Listen Up!
Listen Up!

Listen Up! is a series of arts workshops in Bradford, Leeds and Durham who came together to share experiences, challenge stigma and create artwork for this exhibition that sends a positive message to other young voice-hearers and their families. The artists are Amina Mohammed, Enie Rebecca Hobson, Imogen Godwin, Jai/Jess Mico, Jamie Sykes, Jenna Hullah, Niamh Pitwood, S. H.,  and V. French.

Country
United Kingdom of Great Britain and Northern Ireland

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Literary Voices
Literary Voices

Literary Voices is an exhibition signalling that they are key features to literature as sources of inspiration, through their representation, and in how they are received.

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Suffering
Suffering

Suffering provides individual stories of and responses to suffering are important in developing and expanding knowledge and understanding of voice-hearing. Both positive and negative responses to these stories have profoundly changed attitudes to voice-hearing – cultural, social, legal, and medical. These have, in turn, had significant consequences for voice-hearers.

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The Isle is Full of Noises
The Isle is Full of Noises

The Isle is Full of Noises is a sound and animation installation that explores what it is like to hear voices. It is largely based on a workshop held in summer 2016 in Durham with people who hear voices. The workshop reinforced the need to challenge widespread prejudice about voice-hearing, and to assert that not only is this a normal phenomenon, but that ‘we are people, that have lots of other things going on; voice-hearing is just a tiny part of that’.

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Visionary Voices
Visionary Voices

Visionary Voices are podcasts about the links between voice-hearing and spirituality and then scroll down to see some of the key displays in this section of the exhibition.

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Jacqui Dillon
Jacqui Dillon

Jacqui Dillon is a writer, campaigner, international speaker and trainer. She has personal and professional experience, awareness and skills in working with trauma and abuse, dissociation, ‘psychosis’, hearing voices, healing and recovery.

Beck Road Alliance (BRA)
Beck Road Alliance (BRA)

The Beck Road Alliance (BRA) exists to support survivors of organised childhood sexual abuse on Beck Road, Hackney, and ALL survivors EVERYWHERE, to share their testimonies of surviving childhood sexual abuse. BRA believes that by sharing our experiences, we’re showing the world that the reality of childhood sexual abuse is a global epidemic, which profoundly effects girls and boys. BRA believes that breaking the silence about childhood sexual abuse is crucial in terms of healing from the impact of, and drawing attention to, the widespread prevalence of abuse. Our silence will not protect us. Only the truth will set us free. BRA believes that it is the mark of a responsible society (and responsive services), to honour those experiences, support them and learn from them at all levels.  Only then can we stop the cycle of abuse and prevent future generations from being left with the lifelong legacy of surviving childhood sexual exploitation.

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Conferences
Conferences

Jacqui Dillon is an experienced and accomplished public speaker. I have spoken at numerous national and international conferences and events for both statutory and non-government organisations. She has been a keynote speaker at a variety of events on a diverse range of subjects. Her specialist areas of expertise are:

  • Personal experiences of ‘madness’ and recovery
  • Hearing voices and ‘psychosis’
  • Critiquing biomedical approaches to madness and distress
  • Trauma and abuse
  • Ritual abuse
  • Dissociation and multiplicity

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Consultancy
Consultancy

Jacqui Dillon can offer her unique perspective of working with and making sense of profound distress and extreme states of mind and the impact it has on individuals, teams and organizations. She also have extensive experience in working collaboratively, creatively and in partnership with disempowered and disenfranchised individuals and groups to bring about sustained and lasting improved positive outcomes. Jacqui has provided coaching and mentoring, supervision and consultancy to individuals, teams and organisations.

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Training
Training

Jacqui Dillon provides training based on extensive personal and professional experience, knowledge and skills. All training is experiential enabling participants to develop a deeper understanding and greater insight by exploring experiences from both a subjective and objective perspective. All training is bespoke so it can be tailored to meet the needs of your organisation. Previous courses include:

  • Hearing Voices Awareness
  • Advanced Skills in Working with Voice Hearers
  • Hearing Voices Group Facilitation & Network Development
  • Beyond Survival – Working with Survivors of Childhood Sexual Abuse
  • Abuse, Trauma and Dissociation: Understanding and Working Towards Recovery
  • Advanced Complex Trauma and Working with Sex Workers
  • Ritual Abuse: Thinking About the Unthinkable
  • Working with Self Harm
  • Service User Involvement & User Led Initiatives
  • Helping the Helpers: How Best to Support Your Loved One – For Carers, Allies & Familes
  • Vicarious Traumatisation: Roles, Power and Safety in the Healing Process
  • Therapeutic Use of Self: Path of the Wounded Healer

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Listening to the Silences
Listening to the Silences

Listening to the Silences is a website promoting a book written by Roy Vicent, Listening to the Silences.
 

 

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Country: United Kingdom of Great Britain and Northern Ireland

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Living Life Gently
Living Life Gently

Living Life Gently is a blog created by Elisabeth Svanholmer has worked since 2006 as a Danish Hearing Voices Network trainer and facilitator. Her own experiences of living with voices and other unusual experiences has served as an inspiration for her current work-life. Elisabeth has facilitated training on the hearing voices approach, mindfulness and understanding the highly sensitive person in Denmark, UK, Canada, US and Australia. She has co-facilitated a mindfulness group, a hearing voices group as well as a monthly arts and wellbeing sessions in Calderdale, West Yorkshire. The blogs come under the following topics:

  • Mental Health
  • Sensitivity
  • Bodywork
  • Hearing Voices
  • Creativity
  • Compassion
  • Psychosis and
  • Mindfulness

 

Organisation

Email: svanholmer81@gmail.com

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Madness Radio
Madness Radio

Madness Radio: Voices and Visions From Outside Mental Health is a regular FM show produced through WXOJ-LP in Northampton MA, and aired on KWMD in Anchorage Alaska, KBOO in Portland Oregon, and several other stations. Madness Radio is syndicated through the Pacifica community radio network and shows are picked up by stations around the country and internationally. The show is also vailable online and through iTunes. Hour long shows are produced monthly, with a special 30-minute version also available.

  • Madness Radio
  • Shows Archive

An hour-long interview format, Madness Radio focuses on personal experiences of ‘madness’ and extreme states of consciousness from beyond conventional perspectives and mainstream treatments. Madness Radio also features authors, advocates, and researchers on madness-related topics, including civil rights, science, policy reform, holistic health, history, and art. Madness Radio presents voices often marginalized by other media, and takes a critical approach to mental health policy, corporate marketing, and institutional medical science. Each in-depth interview challenges listeners to a new understanding of experiences that are often stereotyped and feared, and encourages reconsideration of how to improve care and truly meet human needs. The show respects all treatment and medication choices people make, while providing an opportunity to hear outsider perspectives and overcome misinformation. Madness Radio is part of the international movement for diverse-ability rights, informed consent, and self-determination, and envisions a community development rather than medical approach to human emotional distress.

Broadcasting regulary since 2005 (recently producing our 100th show), Madness Radio is co-sponsored by peer run mental health communities Freedom Center, The Icarus Project, and Portland Hearing Voices. Host Will Hall was diagnosed with schizoaffective schizophrenia and works as an advocate, counselor, and educator internationally. Will is co-founder of Freedom Center, a past co-coordinator of The Icarus Project, and assistant director of Portland Hearing Voices, as well as being one of the original organizers that got Valley Free Radio started.

 

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Medical.Net Schizophrenia
Medical.Net Schizophrenia

News-Medical.Net provides the latest Schizophrenia News and Research. It aims to segment, profile and distribute medical news to the widest possible audience of potential beneficiaries worldwide and to provide a forum for ideas, debate and learning, and to facilitate interaction between all parts of the medical health sciences community worldwide.

 

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Open Minded Online
Open Minded Online

Open Minded Online is a website dedicated to sharing ideas and resources about holistic approaches to emotional and social wellbeing

 

Organisation

Country: United Kingdom of Great Britain and Northern Ireland

Email: openmindedtraining@gmail.com

Call +44 (0)7926685432

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Open The Doors
Open The Doors

Cambridge University Press has published “Fighting the Stigma Because of Mental Illness”, a summary of the WPA Global Programme to Fight the Stigma and Discrimination because of Schizophrenia. In 1996, the World Psychiatric Association (WPA) embarked on an International Programme to Fight the Stigma and Discrimination because of Schizophrenia.

The WPA International Programme is designed to dispel the myths and misunderstandings surrounding schizophrenia. Stigma creates a vicious cycle of alienation and discrimination which can lead to social isolation, inability to work, alcohol or drug abuse, homelessness, or excessive institutionalization, all of which decrease the chance of recovery. The programme will fight the prejudice in all walks of life because it diminishes the quality of life of people with schizophrenia and their families and prevents them from living and working among us. The WPA programme is designed to:

  • Increase the awareness and knowledge of the nature of schizophrenia and treatment options;
  • Improve public attitudes about those who have or have had schizophrenia and their families;
  • Generate action to eliminate discrimination and prejudice.
Family & Friends
Family & Friends
  • Family & Friends
  • Message to Caregivers
  • Facts
  • Myths
  • Causes of Schizophrenia
  • How the Brain Operates Differently
  • Stepping Stones for Recovery
  • Reintegration
  • Schizophrenia at School
  • Links to Resources

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Local Action Groups
Local Action Groups

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Open Door Materials
Open Door Materials

The following materials were developed as tools to implement the WPA Programme to Reduce the Stigma and Discrimination Because of Schizophrenia. They are available for programme participants to customize to fit local culture and programme needs. The information from the WPA Programme to Reduce Stigma and Discrimination because of Schizophrenia has been divided into five volumes, available below.

  • Updated Bibliography 2006: a revised bibliography of books and journal articles on Stigma and more specifically on the Stigma associated with mental illness is now available here as well. The bibliography, authored by Professor Norman Sartorius and Dr. Marion Aichenberger is one of the most comprehensive on this important subject.
  • Training Manual: The Training Manual of the WPA “Open the Door” programme includes information on “Assessing Feasability”, “Developing Reasonable Goals and Objectives”, “Working with Community Neighborhoods” and other topics of great importance to those developing a stigma programme.
  • Volume I: Guidelines for Programme Implementation. Outlines a series of steps for developing a programme to reduce stigma and discrimination because of schizophrenia and includes an estimate of the time needed to complete each step. While it is expected that the time required may vary from site to site, it is recommended that sites follow the sequence as specified and complete all steps.
  • Volume II: information about Schizophrenia Relevant to Programme Implementation. Contains facts about schizophrenia selected on the basis of their relevance to such programmes. In this part of the programme document, messages of particular relevance to the reduction of stigma and discrimination are highlighted in the margins. The information in Volume II will be updated regularly to reflect new research findings and the experience of those participating in the programme at different sites
  • Volume IV: Compendium of Programmes Aiming to Reduce Stigma and Discrimination Because of Schizophrenia or Mental Illness in General. Contains information on anti-stigma programmes world-wide engaged in fighting mental illness stigma and discrimination. This compendium collects and reviews information on existing programmes and materials, in order to help those implementing the WPA Programme design their own project, and decide on the media materials to be used. The survey is ongoing and it is expected that many more programmes will be included as information about them is received. Additions will be published as supplements to this compendium.
  • Volume V: annotated List of Materials for use in Country Programmes. This volume is an annotated list of materials used in country anti-stigma programmes. The materials are indexed alphabetically by title, author, audience, media, and language.

 

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Schizophrenia Professionals
Schizophrenia Professionals
  • Symptoms of Schizophrenia
  • Negative Symptoms
  • Causes of Schizophrenia
  • Inheritance
  • Treatment
  • Public Health Problem
  • Links to Healthcare Professionals

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Paranoid Thoughts
Paranoid Thoughts

Paranoid Thoughts is a website is all about unfounded or excessive fears about others. Such fears may be refered to as 'paranoid thoughts' or 'paranoia'. The focus of this website is not on justified anxieties about others, but rather on exaggerated or unfounded fears - fears for which there is little or no convincing evidence. Exaggerated worries about others don't help us stay safe but instead can bring all manner of distress.  This website puts the experience of paranoia centre stage. It was set up in 2006 to mark the publication of the first self-help book on the topic, Overcoming Paranoid and Suspicious Thoughts. The book shows readers how they can use techniques based on the talking therapy CBT to cope with their paranoia (these techniques have been shown to be highly effective in reducing paranoia).

Assess Your Own Paranoia
Assess Your Own Paranoia

Assess your paranoia is a survey with the results from the survey being revealed.

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Getting Help for Paranoia
Getting Help for Paranoia

Paranoid Thoughts recommend reading Overcoming Paranoid and Suspicious Thoughts. This provides extensive information to help people understand exaggerated or unrealistic suspiciousness. Further, six practical steps are provided to help people cope with such fears. However, people sometimes want to consider other sources of help - perhaps seeing a therapist or trying medication. Or sometimes people simply want to find out a bit more about the issues.

So how do we know when it's right to ask for professional help?

There's no cut and dried answer to this one, but basically it boils down to:

  • How much distress the thoughts are causing
  • How much disruption the thoughts are causing on work, relationships, activities, or quality of life

If you do decide to seek professional help, it's crucial that you find the right person. If you think your GP doesn't understand paranoid thoughts and their treatment, ask to be referred to a specialist. It's relatively easy to get knowledgeable advice on medication, but harder to find someone with specialist psychological knowledge. In this section there is information on Cognitive Behaviour Therapy (CBT) & Medication.

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What is Paranoia?
What is Paranoia?

Paranoid Thoughts this website is not on justified anxieties about others, but rather on exaggerated or unfounded fears - fears for which there is little or no convincing evidence. Exaggerated worries about others don't help us stay safe but instead can bring all manner of distress.

What is paranoia?

We could have called this section: What are fears about others? We could also have titled it: What are paranoid feelings? Or: What are persecutory beliefs? Some people use the terms delusional thoughts or, for severe instances, persecutory delusions. The feelings discussed in this website, then, go by a variety of names. Partly this is because paranoia is a term that covers a wide spectrum of experiences. What we mean is:

  • The fear of something bad happening
  • The idea that others may intend to cause such an event>
  • The thought is exagerrated or unfounded.

These fears normally contain certain elements: a perpetrator, a type of threat, and a reason. We can suspect absolutely anyone of wanting to do us harm. Often the perpetrator is a neighbour, stranger, work colleague or family member. Occasionally it may be government organisations or spirits. Sometimes the identity of the person trying to cause the harm is unknown. The type of harm varies too. But typically the fear is of physical, psychological, social or financial harm. Why do people think others are targeting them for harm? Sometimes there's a feeling of simply being a victim, sometimes it is suspected that we're at risk because of who we are, and sometimes it because we think the threat is provoked by something we've done.

How can we tell whether our suspicious thoughts are justified?

How can we tell whether our worries are justified or not? Well, it's not always easy. If you're struggling to decide whether your suspicious thoughts are justified, ask yourself the following questions:

Would other people think my suspicions are realistic?

What would my best friend say?

Have I talked to others about my worries?

Is it possible that I have exaggerated the threat?

Is there any indisputable evidence for my suspicions?

Are my worries based on ambiguous events?

Are my worries based on my feelings rather than indisputable evidence?

Is it very likely that I would be singled out above anyone else?

Is there any evidence that runs contrary to my suspicions?

Is it possible that I'm being at all over-sensitive?

Do my suspicions persist despite reassurance from others that they are unfounded?

 

What are the causes of paranoia?

Research has identified five main factors involved in the occurrence of suspicious thoughts. All five factors are very common - all of us will have experienced at least some of them. What's important though is the way they combine. Suspicious thoughts are caused by a combination of some or all of these five factors:

  • Stress and major life changes. This includes difficult relationships with others at home or at work, and becoming isolated.
  • Negative emotions such as anxiety and depression. Often when we are anxious we can overestimate the chances of threat and worry too much
  • The way we feel has a big influence on the way we think.
  • Internal unusual feelings. Stress can often cause strange feelings (eg. feeling odd, aroused, threatened), as can going without sleep. Sometimes people can feel odd because they have taken drugs such as cannabis.

Our explanations. Paranoid thoughts are our way of trying to understand things. They are attempts to make sense of events. It's perfectly natural to try to understand the world around us - and the way we feel inside. But when we're stressed and feeling low or anxious or irritable our explanations are likely to be pretty negative. We think the worst - and often we think the worst of people around us. It can seem as if the odd or unpleasant things we've been experiencing are deliberately caused by other people.

Reasoning (the way we think things through and come to decisions and judgements). Often suspicious thoughts can take a grip if we do not think of alternative explanations for events, and do not fully consider the evidence for and against our worries. This is sometimes called jumping to conclusions. So, when we are stressed and things are perhaps not going too well, we can become anxious and interpret how we feel in terms of threat from other people, without fully weighing the evidence or considering alternative explanations.

 

How common is paranoia?

Until very recently - the last 15 to 20 years in fact - no one suspected just how many people had paranoid thoughts. But several research projects have now lifted the lid - and the results are striking. Here are just a few statistics from some of those research projects.

In a survey of 8580 UK adults, 21% said there'd been times over the past year when they'd felt people were against them. 9% said they'd believed that their thoughts were being controlled or interfered with by some outside force or person. 1.5% said there'd been times when they'd felt people were plotting to cause them serious harm.

A study of 1005 adults in New York found that 10.6% believed other people were following or spying on them. 6.9% thought people were plotting against them, or trying to poison them. 4.6% believed people were either secretly testing them, or experimenting upon them.

A French survey of 462 adults found that 25% had, at some point in their lives, felt that they were being persecuted in some way. 10.4% had sometimes believed there was a conspiracy against them.

A study of 1202 British university students (aged 16 to 61) assessed their feelings over the previous month. 42% said that, at least once a week, they had thought that negative comments about them might be circulating. 27% had felt that people were deliberately trying to irritate them, and 19% had thought that they might be being observed or followed. 5% thought there might be a conspiracy against them.

More than a thousand older adults (aged 55 and above) in Brooklyn, New York were assessed. 13% had, in the previous week, experienced paranoid thoughts.

Paranoia, then, is widespread - so widespread, in fact, that around 15 to 20% of the population have frequent paranoid thoughts. Most of those people aren't much troubled by their suspicious thoughts. But a further 3 to 5 % have pretty severe paranoia. For this smaller group of people, their paranoia is often serious enough to need specialist treatment.

 

Overcoming paranoia

Look after yourself. We're more likely to be troubled by paranoia if we're tired or run-down or very stressed. So make sure you eat healthily, get plenty of good-quality sleep, and exercise regularly. Make time too for things you enjoy: the more positive activities you have in your life, the less scope there'll be for paranoia to take hold.

Drinking too much, and using illicit drugs, can sometimes trigger paranoid thoughts. If you think they may be a factor in your paranoia, cut back or stop completely.

Consider the pros and cons. As we've seen, underlying paranoia is a fundamental decision about whether or not to trust other people. As a device to help you explore your own approach to this issue, make a list of the pros and cons of both trusting people and mistrusting them. Have you got the balance right, do you think? Would you like to be less mistrustful? Are there experiences from your past that might be having too great an influence on how you see people now

Share your fears. We know that people who don't talk about their paranoid thoughts generally find them more upsetting. So confide in someone you trust. Getting another perspective on your worries can be really helpful.

Get to know your paranoia. Like all problems, it's much easier to cope with our paranoid thoughts if we have a clear picture of them. So for the next seven days keep a diary of your paranoid thoughts - what they are, when they occur, and what might trigger them.

You may well find that particular situations tend to spark your paranoia (perhaps being very anxious or angry or bored, for example). And that will give you the chance to think how you can prevent these situations occurring, or at least how to deal with them better.

Incidentally, one of the great benefits of keeping a diary is that it gets your paranoid thoughts out of your head and onto paper. For many people, that can be a huge relief, and a terrific way of putting some distance between themselves and their paranoia.

Manage your worry. Worry is a very common reaction to paranoid thoughts. People fret about the harm they think other people intend towards them, and sometimes they also worry about what having these thoughts might mean (for example, that they're going mad). But the more we worry, the more anxious and fearful we become. Worry feeds on worry.

So we need to learn to manage our worry. One very useful technique is to save up all your worrying for one half-hour session every day: your worry period. And instead of worrying, try focusing your energy on solving the problem that's troubling you.

Challenge your paranoid thoughts. Choose a suspicious thought from your paranoia diary, and weigh up the evidence for and against it. Ask yourself these questions:

Is there anything that might suggest the thought is wrong?

What would my family or friends say if I talked to them about the thought?

What would I say to a friend who came to me with a similar problem?

Are there any alternative explanations for what seems to have happened?

Are my thoughts based more on the way I feel than on solid evidence?

Have I been jumping to conclusions?

If I were feeling happier or less anxious or less tired, would I still see things in the same way?

Test out your thoughts. Paranoia can make people so anxious and afraid that they change their behaviour, avoiding the situations that trigger their fears. But this only reinforces their paranoia, because it robs them of the chance to discover whether or not their fears are justified.

Testing out your paranoid thoughts involves actively seeking out the situations you're afraid of. That can be pretty nerve-wracking, so you need to go carefully. Draw up a list of tasks you find difficult and start with the relatively easy ones. Once you're comfortable with those, gradually work your way up to the more difficult tasks.

Incidentally, don't put yourself in situations where you're likely to be at real risk. You may be worried about going out alone, for instance, but don't test this by going into a dangerous neighbourhood at night. Concentrate on activities that most people would find reasonable and where you think your suspicious thoughts are probably exaggerated.

Let go of your paranoid thoughts. We're bound to have suspicious thoughts from time to time. It's unrealistic to think we can put a complete stop to them, but we can improve the way we deal with these thoughts when they do occur.

The trick is not to focus on them, to develop what's known as a mindful attitude. Don't fight your thoughts and don't spend time thinking about them. Try to be detached. Watch the thought come to you, remind yourself that it doesn't matter, and let it go off into the distance. Concentrate on what you're doing, rather than what you're thinking.

People often find it helps to repeat an encouraging phrase to themselves, for example "They're only thoughts - they don't matter"; "Keep going - you're doing really well"; "These thoughts don't scare me. I can cope."

 

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Postpartum Psychosis For Carers Royal College of Psychiatrists
Postpartum Psychosis For Carers Royal College of Psychiatrists

Postpartum Psychosis for Carers is a page that aims to explain the symptoms of Postpartum Psychosis and to describe the care and treatment available.  The checklists at the end are tools to help families and health professionals communicate well while someone recovers from Postpartum Psychosis.

 

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Psychosis Links
Psychosis Links

Psychosis Link is a blog created by Philip Benjamin, an Australian mental health nurse. The website provides information and items of interest, support and research regarding psychosis (and schizophrenia) on the web.

 

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Ron Coleman
Ron Coleman

 

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Rufus May
Rufus May

Rufus May is a British clinical psychologist best known for using his own experiences of being a psychiatric patient to promote alternative recovery approaches for those experiencing psychotic symptoms.

 

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Sarah K Reece
Sarah K Reece

Sarah K Reece's website is dedicated to art, writing and community development. Her website is her online home dedicated to Creativity, Diversity, & Inclusion. Sarah offers a number of services including:

  • Creative Workshops: inclusive, safe creative workshops for a range of mediums such as inks, paints, books and zine making, writing, poetry, and small sculpture. These can be specific to a particular community (such as a mental health support group in prison), or to a project such as an inclusive community engagement process.
  • NDIS Support Work & Mentoring: a qualified Mental Health Peer Worker and specialise in supporting adults with diverse identities and experiences, including LGBTIQA+, neurodiversity, trauma and ‘severe and enduring mental illness’. She offers both in person and online chat/email/video support, can provide casual or once off support (for example for a distressing medical procedure), and can accept private non-NDIS clients, build capacity via training other family and support workers, and provide support to professional staff.
  • Consulting
  • Community engagement: using peer based experience to support people engage, recruit, train, and utilise diverse lived experience in your projects and workforce. She also offer support with design/co-design, facilitation, writing, and research.
  • Speaking
  • Training
  • Workshops
  • Board Representation
  • Illustrations
  • Art Exhibitions, Residencies, and Projects
Stand With Jay
Stand With Jay

Jay is an amazing person who exists at the intersections of many disabilities, diversities, and identities that expose them to stigma and discrimination. They were severely let down by the systems that should have supported and protected them. 

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Country: Australia

Postal Address: PO Box 165, Brompton, South Australia, Australia 5007

Email: sarah@di.org.au

Call 0401 099 174

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Schizophrenia Bulletin
Schizophrenia Bulletin

Schizophrenia Bulletin seeks to review recent developments and empirically based hypotheses regarding the etiology and treatment of schizophrenia. They view the field as broad and deep, and will publish new knowledge ranging from the molecular basis to social and cultural factors. 

 

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Schizophrenia Forum
Schizophrenia Forum

 

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Schizophrenia Research
Schizophrenia Research

Schizophrenia Research is the official journal of the Schizophrenia International Research Society (SIRS). Schizophrenia Research is THE journal of choice for international researchers and clinicians to share their work with the global schizophrenia research community with more than 6000 institutes having online or print (or both). The journal publishes novel papers that really contribute to understanding the biology and treatment of schizophrenic disorders; Schizophrenia Research brings together biological, clinical and psychological research in order to stimulate the synthesis of findings from all disciplines involved in improving patient outcomes in schizophrenia. Available article collections, special issues and supplements published within the journal include:

  • Sleep Pathology in Schizophrenia and the Psychosis Spectrum
  • The Retina in Schizphrenia and Related Disorder
  • Genomics and Epigenomics of Schizophrenia
  • Machine Learning in Schizophrenia
  • Stress and Schizophrenia
  • Neuroplasticity and Dysplasticity in Schizophrenia
  • Childhood Trauma and Psychosis
  • Cognitive Therapies for Schizophrenia
  • Neuromotor Pathology in Schizophrenia
  • Impaired sensorimotor Gating in Schizophrenia
  • Accelerated Aging in Schizophrenia
  • Addictions and Schizophrenia
  • Mismatch Negativity
  • Mitochondrial Dysfunction in Schizophrenia
  • Negative Symptoms
  • Pathologies of the Thalamus in Schizophrenia
  • Post-mortem Pathology in Schizophrenia
  • Oxidative Stress and Inflammation in Schizophrenia
  • Progressive Brain Tissue Loss in Schizophrenia
  • Reproductive hormones and schizophrenia
  • The GABA System in Schizophrenia: Cells, Molecules and Microcircuitry
  • Endophenotypes in Schizophrenia
  • White Matter Pathology
  • DSM-5
  • Cognition in Schizophrenia: Presentations from the 2007 ICOSR Cognition Satellite meeting.

 

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Schizophrenia.Com
Schizophrenia.Com

Schizophrenia.com is an internet community dedicated to providing high quality information, support and education to the family members, caregivers and individuals whose lives have been impacted by schizophrenia. This web community was founded in memory of John Chiko, who suffered from schizophrenia. We are dedicated to improving the lives of all individuals and families suffering from schizophrenia, and in speeding the research progress towards a cure.  Schizophrenia.com is a place where family members, friends, people with schizophrenia, researchers, and other professionals come together to share information and experiences in the common battle against this disease There objectives are:

  • To quickly improve the lives of individuals and families suffering from schizophrenia by providing high quality (science-based) information, as well as support and education, research and discussions on all relevant topics.
  • To more widely and quickly disseminate schizophrenia research and information so that treatment techniques, medications or cures can more rapidly be identified and adopted so that the lives of people with schizophrenia are more quickly improved.
  • To facilitate communication between the different schizophrenia stakeholders ( i.e. the schizophrenia research groups, the support organizations and the families around the world suffering from schizophrenia) to improve the understanding and flow of mutually beneficial information between all of the groups.
  • To create a comprehensive Schizophrenia Information service, and to make this service available to as broad an audience as possible, so as to maximize the benefit that this information will have to people around the world.
  • To provide valuable, timely and accurate information on schizophrenia. 

The site is managed by a group of independent volunteers and contractors around the world – most of whom are either family members (with sons and daughters, brothers and sisters, or parents who have suffered from schizophrenia) or people who have schizophrenia. While most of our writers are students of psychiatry, psychology and neuroscience, for the most part we are not full-time working mental health professionals but we are very familiar with the disease both through direct personal experience and extensive reading on the topic.

They rely upon what we believe are good sources of scientifically accurate materials relating to schizophrenia and frequently consult with an ever growing group of schizophrenia researchers who act as unofficial advisors to the site. We owe a great debt of gratitude to the schizophrenia researchers who help on an unofficial basis by answering our questions and occasionally providing feedback on different areas of the site, and these researchers include (but are not limited to) the following:

 

Advocacy - Helping People that have Schizophrenia
Advocacy - Helping People that have Schizophrenia

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An Introduction to Schiozophrenia
An Introduction to Schiozophrenia

An Introduction to Schizophrenia provices an overview and introduction of schizophrenia and paranoid schizophrenia

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B-Vitamins for Schizophrenia
B-Vitamins for Schizophrenia

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Causes of Schizophrenia
Causes of Schizophrenia

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Choline During Pregnancy for Schizophrenia Prevention
Choline During Pregnancy for Schizophrenia Prevention

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D-Alanine for Schizophrenia
D-Alanine for Schizophrenia

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D-serine for Schizophrenia
D-serine for Schizophrenia

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Family and Caregiver Schizophrenia Discussion Forum
Family and Caregiver Schizophrenia Discussion Forum

Family and Caregiver Schizophrenia Discussion Forum is a support and discussion forum for people who are family members or caregivers of someone who has have been diagnosed with schizophrenia, or who might have schizophrenia (or who have a closely related disorder or symptoms, or who suffer from hearing voices).

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Famous People and Schizophrenia
Famous People and Schizophrenia

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Frequently Asked Questions and Answers
Frequently Asked Questions and Answers

Frequently Asked Questions and Answers is rthe questions commonly posted on our discussion boards, along with answers and advice from responding members. In many cases, member answers have been expanded on from other sources, and relevant links have been addedfor more information. These answers are meant only as a helpful guide and a resource for further information; each individual situation is unique and may need a tailored solution. Your treating psychiatrist is always a good person to ask when you have specific questions pertaining to your own case.

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Marijuana / Cannabis and Schizophrenia
Marijuana / Cannabis and Schizophrenia

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Melatonin for Schizophrenia
Melatonin for Schizophrenia

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N-Acetyl cysteine (NAC) for Schizophrenia
N-Acetyl cysteine (NAC) for Schizophrenia

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Omega 3 for Schizophrenia Prevention
Omega 3 for Schizophrenia Prevention

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Overcoming Depression
Overcoming Depression

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Overview of Schizophrenia
Overview of Schizophrenia

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Personal Success Stories of Coping with Schizophrenia
Personal Success Stories of Coping with Schizophrenia

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Preventing Schizophrenia - Tactics and Risk Reduction Strategies
Preventing Schizophrenia - Tactics and Risk Reduction Strategies

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Preventing Suicide in People who have Schizophrenia
Preventing Suicide in People who have Schizophrenia

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PRIME Screening Test
PRIME Screening Test

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Schizophrenia and Poverty, Crime and Violence
Schizophrenia and Poverty, Crime and Violence

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Schizophrenia Biology and Genetics
Schizophrenia Biology and Genetics

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Schizophrenia Facts & Statistics
Schizophrenia Facts & Statistics

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Schizophrenia Handbook For Advice and Support
Schizophrenia Handbook For Advice and Support

The Schziophrenia Handbook For Advice and Support is a free handbook for people affected by schizophrenia and psychosis has been launched recently by Schizophrenia Ireland. "Discover the Road Ahead" is a comprehensive and user-friendly handbook that gives people with schizophrenia and their families information, advice and support. Its easy to read, and a good primer for people new to the issues associated with schizophrenia, or simply those who want a quick reminder of how to handle issues that come up frequently. (Note: Schizophrenia Ireland also has a very good booklet on suicide prevention as it relates to schizophrenia)

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Schizophrenia Pictures and Images of Brains
Schizophrenia Pictures and Images of Brains

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Schizophrenia Recovery and Coping Resources
Schizophrenia Recovery and Coping Resources

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Schizophrenia Reference Library
Schizophrenia Reference Library

The Schizophrenia Reference Library is an online PDF reference library, a compilation of mental illness information and literature from our own site and from external sources. They are all in pdf format, ready and available for downloading and printing. Most of them are brief, easy-to-read articles, ideal for passing out to family, friends, teachers, employers, or anyone else that might benefit. Some are longer documents that may take a few minutes to download. Please note that in its early phases the delusions, confusion and other symptoms that are common to schizophrenia are generally refered to by the more general term of "psychosis"

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Schizophrenia Research and New Drug Clinical Trials
Schizophrenia Research and New Drug Clinical Trials

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Schizophrenia Support Groups and Related Resources
Schizophrenia Support Groups and Related Resources

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Schizophrenia Symptoms
Schizophrenia Symptoms

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Schizophrenia Treatment
Schizophrenia Treatment

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Schizophrenia-related Events, Conferences and Activities
Schizophrenia-related Events, Conferences and Activities

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Smoking and Schizophrenia
Smoking and Schizophrenia

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Worldwide Early Diagnosis & Treatment Centers for Psychosis & Schizophrenia
Worldwide Early Diagnosis & Treatment Centers for Psychosis & Schizophrenia

Worldwide Early Diagnosis & Treatment Centers for Psychosis & Schizophrenia is a list of clinics around the world that specialize in early diagnosis and treatment for schizophrenia and psychosis (delusions, etc). If you are concerned that you or a person you know is at risk for, or may be developing psychosis or schizophrenia we recommend you call today the clinic closest to you, to schedule an appointment. 

  • Clinics
  • Psychiatric Treatment Centers Affiliated with Medical Schools in the USA
  • Top 10 US Psychiatric Hospitals

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Schizophrenic.com
Schizophrenic.com

Schizophrenic.com is a growing online community for those who are looking for help with Schizophrenia. Their goal is to bring people together around life's challenges by providing concise, up-to-date information and a meeting place for individuals, their friends and families, and professionals who offer pathways to help. This includes topics such as:

  • Schizophrenia Symptoms
  • Schizophrenia Treatment
  • Schizophrenia Therapy
  • Schziophrenia Research
  • Autism
  • Catatonic Schizophrenia
  • Causes of Schizophrenia
  • Childhood Schizophrenia
  • Crime & Violence
  • Depression
  • Diagnosis of Schizophrenia
  • Disorganised Schizophrenia
  • Health Issues & Schizophrenia
  • Managing Schizophrenia
  • Mental Health
  • Natural Treatments for Schizophrenia
  • Paranoid Schizophrenia
  • Prevention of Schizophrenia
  • Smoking & Schizophrenia
  • Suicide
  • Teen Schizophrenia
  • Vitamin D & Schizophrenia
Causes of Schizophrenia
Causes of Schizophrenia

Despite a significant amount of research, science has yet to reveal exactly what causes schizophrenia. Some experts believe it is a combination of factors, particularly genetics, brain anomalies, and environmental triggers. Others, however, believe that this complex disorder is actually not a single disorder at all, but several different disorders. This can make pinpointing a cause even more challenging.

  • Genetics: since schizophrenic appears to have a strong hereditary component, it is very possible that a person is born with a genetic predisposition towards developing the disorder. We know that individuals who have an immediate family member with the disorder have a 10% or higher risk of becoming schizophrenic, compared to 1% of the general population 1. However, not all of them do. Whether he/she does develop the disorder may depend on environmental factors which then trigger the development of schizophrenia.
  • Environmental Factors: there are many different environmental factors which have been linked to the development of schizophrenia. They are not believed to cause the disorder, in and of themselves, but rather may play a role in its development if the person is already vulnerable. Some of these factors include:
  1. Complications during pregnancy or birth, such as maternal illness, exposure to certain toxins or viruses such as the flu virus, severe maternal stress or malnutrition early in the pregnancy, or a long labor
  2. Serious early childhood infections or a history of seizures
  3. Traumatic or highly stressful life situations, usually in childhood up to early adulthood
  4. Regular marijuana use
  5. Brain abnormalities
  6. Chemical imbalances

Research has shown that some schizophrenics have structural differences in their brains when compared to the brains of normal people. Also, imbalances in brain chemicals known as neurotransmitters likely play a role in many psychiatric disorders, including schizophrenia. Antipsychotic medications typically target either dopamine, or dopamine and serotonin together. There are many more potential factors which may contribute to the development of schizophrenia. As research on schizophrenia continues, hopefully science will eventually show us exactly what causes this serious psychiatric illness. For further information you can explore the following links:

  • Causes of Schizophrenia

  • Schizophrenia Is Caused By A Combination of Factors

  • Signs That Serotonin Plays A Role In Schizophreni

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Managing Schizophrenia
Managing Schizophrenia
  • Why Schizophrenia Has Lead To Homelessness

  • Five Common Variables: Study Reviewed Risk Factors For Self Injury In Schizophrenics

  • Family Relationships

  • Living With Schizophrenia

  • Schizophrenia and the Workplace

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Natural Treatment for Schizophrenia
Natural Treatment for Schizophrenia
  • Art Therapy Not Effective at Treating Schizophrenia

  • New report on acupuncture for schizophrenia

  • Brain "exercise" stimulation might improve memory in schizophrenics

  • Regular Exercise has Mental Health Benefits for Schizophrenics

  • Exercise Could Help Treat Schizophrenia

  • Mental, Physical Exercise Helps Young People With Schizophrenia

  • Exercise Reduces Psychosis Symptoms In Young People

  • Low-Carb Diet Could Help Schizophrenia

  • US funds 160K yoga study for schizophrenia

  • Yoga Therapy for Neuropsychiatric Disorders

  • Exercise Reduces Psychosis Symptoms In Young People

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Prevention of Schizophrenia
Prevention of Schizophrenia
  • Prevention

  • Community prevention program for schizophrenia drops psychosis-related hospitalizations

  • Can Mental Health Disorders Be Prevented With Exercise?

  • Mental health and diet: clean eating could prevent common disorders

  • Fish oil supplements may help prevent psychosis

  • Choline supplements could prevent schizophrenia

  • Family Interventions Help Prevent Relapse in Schizophrenic Patients

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Schizophrenia
Schizophrenia
  • History of Schizophrenia: Where It All Began and How Far We Have Come

  • Causes of Schizophrenia

  • Talented Schizophrenic Musicians Who Succeeded In Life

  • Schizophrenia Pathophysiology: Key Factors In The Development Of Schizophrenia

  • Managing Schizophrenia

  • Types of Shizophrenia

  • What Are The Characteristics and Symptoms of Catatonic Schizophrenic?

  • Why Schizophrenia Has Lead To Homelessness

  • ICD 10 Schizophrenia General Criteria For Diagnosis

  • Five Common Variables: Study Reviewed Risk Factors For Self Injury In Schizophrenics

  • What Are Movement Disorders In Schizophrenia?

  • Signs That Serotonin Plays A Role In Schizophrenia

  • Do Schizophrenics Know They Are Schizophrenic?

  • People Experiencing a Schizophrenic Break Display Outward Symptoms

  • Diathesis Stress Theory: One Established Explanation for Schizophrenia

  • Acute Schizophrenia Responds Better To Treatment Than Chronic Schizophrenia

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Schizophrenia & Genetics
Schizophrenia & Genetics
  • Schizophrenia isn't a single disease, but eight specific genetic disorders

  • Is schizophrenia hereditary?

  • Is schizophrenia genetic?

  • Prenatal Environment Has Stronger Effect on Mental Illness Genes than Others

  • Key to Schizophrenia May Lie Outside Our Genes

  • Biomarker May Bridge the Gap Between Genes and Disease

  • Creativity and Schizophrenia Might Share Genes

  • Genetic Links Found for Schizophrenia, Bipolar Disorder

  • More research supports genetic link between schizophrenia and bipolar disorder

  • Genetic Mutations Provide Clues to Schizophrenia

  • Genetic Mutation Linked to Schizophrenia

  • Schizophrenia Genetics Linked to Disruption in Brain's Processing of Sound

  • Study offers new clues into schizophrenia's genetic code

  • Genetic link found between marijuana use and schizophrenia

  • Scientists Create Genetic 'GPS' System to Locate and Track Nerve Cells

  • Schizophrenia and memory: how a network of genes might influence the development of mental illness

  • Genetic changes identified in onset of schizophrenia

  • Scientists Create Genetic 'GPS' System to Locate and Track Nerve Cells

  • How Our Parents' Stress Can Affect Our DNA

  • Genetic mutation identified in schizophrenia risk

  • Genetic Mutation and Predisposition for Schizophrenia

  • Genetics and Schizophrenia - A Twin Study

  • Single Changes in Two Genes Can Double Schizophrenia Risk

  • Genetic Defects, Stress Linked to Abnormal Brain Development

  • Sleep Disorders, Schizophrenia Share Genes

  • Severe Weight Gain During Anti-psychotic Treatment May Be Genetic

  • New Understanding of Genes Leads to Better Predictive Test for Schizophrenia

  • Schizophrenia and autism share genetic link

  • Genetic mutation identified in schizophrenia risk

  • Genetic changes identified in onset of schizophrenia

  • More research supports genetic link between schizophrenia and bipolar disorder

  • Schizophrenia and memory: how a network of genes might influence the development of mental illness

  • Study offers new clues into schizophrenia's genetic code

  • GABA Genes May Play Significant Role in Schizophrenia

  • Two Genes Provide Clues for Schizophrenia Treatment

  • In Schizophrenia, Health and Cognitive Function May Share the Same Genes

  • Genetic Counseling Helps Schizophrenia Patients

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Schizophrenia Diagnosis
Schizophrenia Diagnosis
  • Diagnosing Schizophrenia
  • Schizophrenia Prognosis

  • Undifferentiated Schizophrenic

  • ICD 10 Schizophrenia General Criteria For Diagnosis
  • DSM IV-TR: Diagnostic Criteria for Schizophrenia

  • Changes in Blood Can Assist in Schizophrenia Diagnosis

  • Closing In On a Diagnostic Test for Schizophrenia?

  • Brain Wave Pattern During Non-REM Sleep Could Help Diagnose Schizophrenia

  • Blood Test May Help with Diagnosing Schizophrenia

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Schizophrenia in Teens
Schizophrenia in Teens
  • Scans Could Predict Onset Schizophrenia in Youth

  • Half of US teens don't get help for mental health problems

  • Family dinners provide better mental health outcomes for teens

  • Talk therapy the best first option for teens with psychosis risk

  • New Clinic Offers Speedy Treatment for Schizophrenic Teens

  • Abilify May be Recommended for Schizophrenic Teens

  • Marijuana-Using Teens Have Higher Risk for Schizophrenia

  • Schizophrenia symptoms in teenage boys

  • A 'teen gene' may influence the development of mental illness

  • A common link found between mental health issues and casual sex in teens

  • Scans Could Predict Onset Schizophrenia in Youth

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Schizophrenia Research
Schizophrenia Research
  • Understanding Schizophrenia

  • Cure For Schizophrenia?

  • Is schizophrenia caused by a virus?

  • New Insight Into the Schizophrenic Brain

  • New Genome Database a Powerful Tool for Brain Research

  • Pharma and Academics Collaborate for Research

  • Schizophrenia Outcomes Influenced By Cognitive Reserve

  • Mapping the Human Brain

  • Neurons That Filter 'Brain Clutter' Identified

  • Automated Mapping of the Whole Brain

  • You can tell a schizophrenic by looking into his eyes--literally

  • Dopamine-Altering Parasite May Yield Mental Illness Treatments

  • New Compounds May Improve Schizophrenia Treatment

  • Improve Cognition With New Neurons

  • Scientists Induce Schizophrenia in a Computerized Brain

  • Brain Changes Occur as At-Risk People Develop Schizophrenia

  • Could brain waves predict schizophrenia?

  • One Mind for Brain Research

  • Questions Raised Over Brain-Harvesting Practices

  • Why Schizophrenics Misunderstand Social Cues

  • Schizophrenia Statistics: Doctors Are Becoming Better At Understanding And Treating The Illness

  • Schizophrenia Case Studies Help Researchers Come Up with New Hypotheses

  • Research May Point to New Drug Targets For Schizophrenia

  • GC-C

  • Eyes Tracking

  • Individuals with Early-Stage Schizophrenia have Better Outcomes when Receiving Both Psychosocial Treatment and Antipsychotic Medication

  • Greater risk of Psychotic Disorders for City Dwellers

  • Serious Mental Illness can Shorten One’s Lifespan by over 14 Years

  • Cognitive Impairment in Schizophrenia Linked to the Cold Sore Virus

  • Recent Survey Indicates Most Schizophrenics Have a Positive Relationship with their Psychiatrist

  • Newly Identified "Switch" For Brain Development Affects Schizophrenia

  • People With Schizophrenia Share Higher Burden of Physical Illness

  • Predictor of Non-remission for First-episode Psychoses

  • Greater risk of Psychotic Disorders for City Dwellers

  • Connection between the Development of Schizophrenia and an Immune Protein

  • New Study May Lead to Advances in the Treatment of Schizophrenia

  • Doctors Discuss Psychosis Risk Syndrome

  • Schizophrenia Gene Mutation May Also Be Responsible for Other Mental Illness

  • Estrogen Being Tested as Schizophrenia Drug

  • Understand Prodromal Psychosis - Early Signs of Schizophrenia

  • Monkeys, Regret and Schizophrenia

  • Reviewing Schizophrenia News

  • Test to Measure Executive Function Proposed for Schizophrenia

  • High-Speed Microscope May Offer Look Into Schizophrenia

  • Research May Point to New Drug Targets For Schizophrenia

  • Scientists Learn More About Brain Building Process

  • Stem Cells Created With Schizophrenia Gene

  • Cellular Bilingualism May Reveal Schizophrenic Secrets

  • Britain's Severely Mentally Ill Die Younger

  • Similar Brains: Epilepsy-Related Psychosis and Schizophrenia

  • Eye Movement Differs By Population, Not Only Disease

  • Coffee and Auditory Hallucinations

  • Early Interventions Not Well Studied

  • City Dwellers At Increased Risk For Schizophrenia

  • Pregnancy Weight Gain and Schizophrenia Risk

  • Antipsychotic Drugs: New Hope For Treating Side Effects

  • Preemies' Abnormal Brain Ultrasounds Linked to Future Psychiatric Disorders

  • Schizophrenia’s Social Deficits Induced in Mice

  • Improving Learning with Brain Stimulation Technique

  • Poor Mental Health Found in 2 out of 5 Europeans

  • Scientific Breakthrough May Lead to Better Drugs for Diseases Like Schizophrenia

  • Schizophrenia and Epilepsy Have Strong Bidirectional Link

  • Brain Continues to Develop Longer Than Previously Thought

  • Real or Imagined? Brain Variation May Explain Why Some People Can't Tell

  • Sociability May Depend on Brain Cells Generated in Adolescence

  • Brain Synapse Development Affected by Wake-Sleep Patterns in Adolescence

  • Growing Schizophrenia in a Petri Dish

  • Virtual Schizophrenic Brains Differ Structurally from Healthy Brains

  • Normal Brain Communication in AgCC Patients

  • Not All VA Care Is Equal for the Mentally Ill

  • Weakened Sense of Body Ownership May Offer New Treatment Options for Schizophrenics

  • Clergy Often Unprepared for Those with Mental Illness

  • Methamphetamine Abuse Linked to Schizophrenia

  • Excessive Gaming Causes Brain Changes Similar to Addicts, Schizophrenics

  • Study: Human Brain Ruled by Small Group of Powerful, “Networked” Areas

  • Fattah Neuroscience Initiative Wins Congressional Support

  • One Mind for Research and the New York Academy of Sciences Team Up to Tackle Alzheimer’s, Dementia

  • GABA Deficits Can Disrupt Endocannabinoid System

  • Study Finds No Link Between Borna Disease Virus and Mental Illness, Ends 30 Year Debate

  • Learning from Others Uses Different Parts of the Brain

  • New Neurochemical Being Called "Master Regulator Molecule" for Schizophrenia

  • Schizophrenia, Other Diseases May Respond to Magnetic Stimulation

  • Cats May Indirectly Cause Mental Illness

  • Computer Training to Aid Schizophrenics' Awareness of Reality

  • Understanding the Prefrontal Cortex's Handling of New Information

  • Virtual Brain Shows How We Use Memory to Make Decisions

  • Danish University to Receive Record-Breaking Grant for Schizophrenia Research

  • Psychotic Disorders May Be Caused by Mitochondrial Defects

  • Dutch Researchers Uncover New Learning Mechanism in Adult Brain

  • Brain Volume Can Predict Huntington's Disease

  • Dopamine May Govern Willingness to Work

  • Finnish Study Explores the Relation Between Epilepsy and Psychosis

  • Redundant, Parallel Brain Channels Help Prevent "Traffic Jams"

  • Schizophrenia May Cause Brain Circuits to Go "Out of Tune"

  • Psychotic Disorders May Be Caused by Mitochondrial Defects

  • Reward Centers of Brain Offer New Target for Neuropsychiatric Treatments

  • 'Brain Glue' Cells More Powerful than First Suspected

  • Everyday 'Mind-pop Events' Linked to Schizophrenic Hallucinations

  • Italy's Decades-Long Record of Poor Schizophrenia Trials

  • Mentally Ill Mothers More Likely to Have Birth Complications

  • Statistics Yield Simply But "Remarkably Complete" Model of Brain

  • Study Finds Gene Controlling Brain Size and Intelligence

  • Different Degrees of Gene Expression May Allow More Personalized Medicines

  • San Francisco Doctor Develops Computer Games to Aid Schizophrenic Brains

  • Mapping Mouse Vision Offers New Understanding of Brain Structure, Mental Disease

  • Scientists Explore Link Between Delusions and Brain Activity in Schizophrenic Patients

  • PCE in Water May Cause Mental Illness

  • Your Nose Is a Breeding Ground for ... Stem Cells?

  • Unused Neurons "Pruned Away" by Immune Cells

  • PERK Protein Found to Regulate Behavioral Flexibility

  • Faster Protein Decoding Method May Speed Drug Development

  • Relatives of Schizophrenics Show Signs of Executive Impairment

  • UC San Diego Receives $4 Million to Study Accelerated Aging, Schizophrenia

  • Using Eye Movement to Predict Schizophrenia

  • A New Computer Program Claims to Reduce Schizophrenia Symptoms

  • Mixed Success in Treating Schizophrenia with Antipsychotics

  • Lilly’s Termination of Developing Schizophrenic Drug

  • Schizophrenia: Taking the Blame?

  • Gene Mutations Discovered

  • 40 Year Study on Mental Illness and Creativity

  • More brain mutations means higher risk for schizophrenia

  • Family history of schizophrenia? You might be at risk for other mental disorders

  • Does schizophrenia cause poor sleep, or could it be the other way around?

  • Does being spiritual predispose you to mental health problems?

  • Deflated hippocampus linked to more severe schizophrenia

  • Schizophrenics have increased risk for pneumonia

  • Verbal decline in adolescence linked to schizophrenia

  • Bad diets may explain why schizophrenics have high metabolic abnormalities and early death rates

  • Schizophrenia might develop during brief window in infancy

  • Have you had your mental health checkup this year?

  • Treatment-resistant schizophrenia tied to ethnicity

  • People with schizophrenia risk have lower IQ scores as they age

  • Bullying linked to psychological problems for both victims and bullies

  • "Sketch pad" in the brain doesn't work for schizophrenics

  • Dad's mental health linked to toddler's emotional and behavioral development

  • Do mental health problems increase risk of death by homicide?

  • Mental health training for police officers shows benefits

  • New condition in DSM-IV could classify millions as mentally ill

  • Scientists deliberately alter mice brain activity and see schizophrenia-like symptoms

  • Schizophrenia doesn't have to impede weight loss, study says

  • Are doctors missing the early warning signs of schizophrenia?

  • Colleges failing at providing adequate mental health resources

  • Smokers with mental illness: are doctors missing the mark?

  • Babies' brain functioning responds to arguments in the home

  • When it comes to mental health issues, social media is underutilized

  • Schizophrenics who relapse more likely to have UTIs, researchers say

  • Google search terms reveal mental health patterns

  • Mania in schizophrenics increase risk of victimization

  • Excess of key neurotransmitter glutamate may cause schizophrenia

  • Scientists say testosterone's role in schizophrenia is important

  • When it comes to schizophrenia, the nose knows

  • Mental health "bible" DSM denounced by US National Institute of Mental Health

  • Stress of mental illness linked to menstrual cycles

  • Can avatars help schizophrenics?

  • Lead exposure and schizophrenia

  • Schizophrenia in a petri dish?

  • Mental workouts for schizophrenia help attention and memory

  • Seeing and hearing in your head can change actual perception, research shows

  • Men in gangs more likely to suffer from mental illness

  • Poor eye movements and schizophrenia

  • Disruption of gene that could double risk for schizophrenia

  • Psychedelic drugs aren’t harmful to mental health, study finds

  • Mental and substance use disorders are leading cause of non-fatal illness, study reveals

  • Faulty switch between brain regions may be the cause of schizophrenic hallucinations

  • Increased mortality in schizophrenia not related to medication, study finds

  • Schizo-OCD: Where Obsession and Delusion Meet

  • Intermodality dysfunction in infants can predict schizophrenia risk

  • Substance abuse lengthens hospital stays for schizophrenics

  • Sleep: too little or too much can lead to mental stress, chronic disease

  • Antihistamine as schizophrenia cure?

  • A hormone could treat symptoms of psychosis, metabolic disease in schizophrenics

  • Mental health is sorely lacking in some US counties, study finds

  • Mental health patients: What if you could read your doctor's notes?

  • If you enjoy adderall, you may have a decreased risk of developing schizophrenia

  • Schizophrenics more likely to die of tobacco use than other individuals, study reports

  • Mothers exposed to trauma may have babies prone to mental illness

  • Schizophrenia patients more likely to have demenita, study reveals

  • Lower brain volume seen in patients with psychotic disorders

  • Mental and substance use disorders are leading cause of non-fatal illness, study reveals

  • Faulty switch between brain regions may be the cause of schizophrenic hallucinations

  • Increased mortality in schizophrenia not related to medication, study finds

  • Schizo-OCD: Where Obsession and Delusion Meet

  • Intermodality dysfunction in infants can predict schizophrenia risk

  • Substance abuse lengthens hospital stays for schizophrenics

  • Sleep: too little or too much can lead to mental stress, chronic disease

  • A blood test for schizophrenia?

  • In the mentally ill, substance abuse is the main cause behind early death

  • Retinal imaging could help identify schizophrenia

  • New study explores weight loss in schizophrenics

  • Omeros announces positive results from schizophrenia drug trials

  • A link between schizophrenia and motor disorders?

  • A 10-minute test for schizophrenia?

  • Schizophrenia raises risk of pregnancy complications

  • More insight into how stress predisposes the brain to mental illness

  • Mental health patients four times more likely to have HIV

  • Schizophrenics more likely to get sick

  • Father's age linked to psychiatric problems in offspring

  • Drug tolerance testing might be getting better for schizophrenics

  • Japan's schizophrenia treatment market set to undergo significant growth

  • Brain-mapping shows schizophrenics have decreased ability to imitate

  • When it comes to schizophrenia treatment, first contact with a provider can make all the difference

  • The number and nature of gene mutations - rather than a single mutation - matter more in schizophrenia

  • Antipsychotic medications can affect babies during pregnancy

  • Maternal blood inflammation linked to schizophrenia

  • Memory impairment in schizophrenia may be due to faulty 'noise filter'

  • Schizophrenics lose brain volume faster with antipsychotic medications

  • Does saliva play a role in schizophrenia?

  • Lack of motivation linked to cognitive performance in schizophrenia patients

  • How the immune system may be linked to mental illness

  • Brain structure prevents schizophrenics from turning goals into action

  • Schizophrenia doesn't mean you can't be happy, study says

  • Alkermes submits applications for schizophrenia drug aripiprazole

  • Obsessive-complusive disorder increases risk for schizophrenia

  • Brain 'folding' pattern could suggest disturbances linked to schizophrenia

  • Problems with working memory makes learning difficult for schizophrenics

  • Patients with psychosis have increased risk of potentially fatal health risks

  • Blood test could determine psychosis risk

  • Ambient Noise May Negatively Impact People With Schizophrenia

  • Groundwork For Schizophrenia May Take Place In The Womb

  • Schizophrenia Linked To Yeast Infections

  • Schizophrenic Patients May Have Shortcomings In Visual And Tactile Processing

  • Brains Of Healthy Relatives May Provide Understanding Of Schizophrenia

  • Brain Inflammation Linked to Schizophrenia

  • Bad Blood Circulation Linked to Psychosis in Alzheimer's Patients

  • This is the Strongest Predictive Sign of Schizophrenia

  • Little Brain Shocks May Help Schizophrenia Patients

  • Schizophrenia May Start In Early Brain Development

  • Schizophrenia's 'Rosetta Stone' Gene Offers Clues for Targeting Treatment

  • Retinal Changes Can Offer Clues About Schizophrenia

  • A Computer Could Predict Psychosis Risk Better Than a Doctor

  • Frontal Brain May Hold Clues Regarding Risk Of Schizophrenia

  • Brains Of Patients With Schizophrenia Attempt Self-Healing

  • Schizophrenia Statistics: Doctors Are Becoming Better At Understanding And Treating The Illness

  • Schizophrenia Case Studies Help Researchers Come Up with New Hypotheses

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Schizophrenia Therapy
Schizophrenia Therapy
  • Benefits of Online Therapy

  • Treating Schizophrenia with CBT

  • Electroconvulsive Therapy (ECT)

  • Electroconvulsive Therapy Could Help Treat Schizophrenia

  • Talk Therapy

  • How to Get Family Therapy for Schizophrenia

  • Cognitive therapy may do just fine for schizophrenia

  • Adherence therapy most effective against schizophrenia relapse

  • FDA Approval Sought For Schizophrenia Therapy Game

  • What is cognitive behavioural therapy?

  • What is cognitive behavioural therapy?

  • Cognitive Therapy for Schizophrenia

  • Psychotherapy for Schizophrenia

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Schizophrenia Treatment
Schizophrenia Treatment
  • Schizophrenia Treatment

  • Schizophrenia Support Groups

  • Schizophrenia and Self Help

  • Drugs for Schizophrenia Treatment

  • Treating schizophrenia without medication

  • Conventional Antipsychotics

  • Early Treatments for Schizophrenia

  • New Generation “Atypical” Antipsychotics

  • Early Treatments for Schizophrenia

  • Side Effects of Antipsychotics

  • Watching Chemical Reactions in the Body May Lead to Faster Drug Development

  • Antipsychotic Mediations: More Expensive May Not Equal More Effective

  • New Generation “Atypical” Antipsychotics

  • Lorazepam as a Treatment for Schizophrenia

  • Does Creatine Benefit Schizophrenia?

  • Acute Schizophrenia Responds Better To Treatment Than Chronic Schizophrenia

  • Cancer Drugs a Promising Schizophrenia Treatment?

  • Immunotherapy Can Boost Cognitive Function in Schizophrenia Patients

  • Risperidone (Risperdal)

  • Clozapine

  • Haldol

  • Fluphenazine

  • Thioridazine

  • Seroquel

  • Quetiapine (Seroquel)

  • What is Trilafon?

  • Mellaril

  • Zyprexa

  • Olanzapine (Zyprexa)

  • Ziprasidone (Geodon)

  • Aripiprazole (Abilify)

  • Abilify approved by FDA for schizophrenia

  • Paliperidone (Invega)

  • Lithium

  • Perphenazine

  • DHEA

  • Asenapine (Saphris)

  • Choline

  • Oxytocin – the “Cuddle Chemical” – May Help Schizophrenic Symptoms

  • Antipsychotic Mediations: More Expensive May Not Equal More Effective

  • Male Schizophrenics May Benefit From Estrogen Treatment

  • Antipsychotic Drug Xeplion Approved in EU

  • New Study Results Favor Risperdal Consta

  • Drug Trial Shows Promise For Negative Symptom Treatment

  • New Treatment Option For Adolescent Schizophrenics

  • Eli Lilly Testing New Schizophrenia Drug

  • ADHD Drug Shows Promise For Negative Symptom Treatment

  • Could Antidepressants Help Treat Schizophrenia?

  • Schizoaffective Disorder Treatment

  • Forced Medication - OK or Not?

  • Choline and Inositol

  • Explanation for Weight Gain with Antipsychotic Use

  • Benefits of DHEA

  • Mental Health Prescriptions at Record Levels, Especially among Women

  • Oxytocin – the “Cuddle Chemical” – May Help Schizophrenic Symptoms

  • Dangerous Blood Clot Risk Linked To Newer Antipsychotics

  • New Drug to Treat Schizophrenia is Approved

  • New Drug Approved for the Treatment of Schizophrenia in Adults

  • Drug in Clinical Trial May Improve Cognitive and Negative Schizophrenia Symptoms

  • Multi-Million Dollar Lawsuits Against Pharmaceutical Companies Selling Antipsychotic Drugs

  • Latuda Further Proves Effectiveness in Schizophrenia

  • Possible Therapeutic Benefits of Ecstasy

  • Top Drug Treatments for Schizoid Personality Disorder

  • New Antipsychotic Drug Usage Growing With Concern

  • Male Schizophrenics May Benefit From Estrogen Treatment

  • Antipsychotic Drug Xeplion Approved in EU

  • New Study Results Favor Risperdal Consta

  • Drug Trial Shows Promise For Negative Symptom Treatment

  • New Treatment Option For Adolescent Schizophrenics

  • New Research Reveals Haloperidol’s Effect on the Brain Structure

  • Could Antidepressants Help Treat Schizophrenia

  • Inhaled Antipsychotic Gets Mixed Reaction from FDA Panel

  • NSAIDs Might Boost Antipsychotic Treatments

  • Metabolic Syndrome in Response to Second Generation Anti-psychotics

  • Schizophrenia and Glutamate Receptors

  • Newly Discovered Mechanism of Action in Dopamine Stabilizers

  • Older Antipsychotics Unsafe for the Elderly

  • Selective Compound Targeting Schizophrenia Gene Receptors Found

  • Taking Ritalin Reduces Performance Errors

  • Accidental Discovery of Glutamate Regulator in the Blood-Brain Barrier

  • Meth Use in Pregnancy Leads to Behavior Disorders in Children

  • Generic Seroquel Receives FDA Approval

  • Anti-Psychotics Rarely the Best First Option for Schizophrenia, Says Study

  • Court: Johnson and Johnson Lied about Anti-Psychotic Dangers, Fined $1.2 Billion

  • Phase 3 Trial Finds Significant Improvement for Parkinson's Patients

  • Schizophrenia Relapse Much Less Likely with Anti-psychotic Drugs

  • Long-term Psychiatric Medications Can Lead to Structural Changes in the Brain

  • Curbing Non-Approved Use of Antipsychotics May Yield Monetary Savings

  • Federal Programs to Reduce Antipsychotic Drug Use in Nursing Homes

  • FDA Accepts Review of Schizophrenia Drug

  • $1.8 Million Awarded to Develop More Effective Drugs for Schizophrenia

  • Schizophrenics who take their meds live longer, study says

  • UCSF swapping drugs for computers to treat schizophrenia

  • Why anti-psychotic drugs don't work for some schizophrenics

  • How to support a schizophrenic

  • Patient recruiting finished for schizophrenia drug trial, treatment aims to address "negative" symptoms of disease

  • Can schizophrenia patients benefit from hypertension drugs?

  • FDA probes 'unexplained' deaths from schizophrenia drug Zyprexa

  • Flexible-dose injection treatment shows promise for schizophrenia

  • Johnson & Johnson recalls schizophrenia drug due to mold

  • A cancer drug shows promise for reversing schizophrenia in mice

  • New drugs and old drugs are same in terms of effectiveness, schizophrenia research suggests

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Symptoms of Schizophrenia
Symptoms of Schizophrenia
  • Schizophrenic Symptoms

  • Identifying schizophrenia: 4 symptoms to look out for

  • Early Symptoms of Schizophrenia

  • Positive Schizophrenia Symptoms

  • Negative Symptoms of Schizophrenia

  • Schizophrenia's Cognitive Symptoms

  • Visual symptoms of schizophrenia

  • Undifferentiated Schizophrenia Symptoms

  • Residual Schizophrenia Symptoms

  • What Are Movement Disorders In Schizophrenia?

  • Schizophrenic Tendencies: Precursor To The Illness

  • In bilingual individuals, schizophrenia symptoms may show up in language

  • Sleep deprivation leads to schizophrenia-like symptoms

  • Sleep Disruption Often Overlooked as Symptom of Schizophrenia

  • Investigational Drug Shows Promise for Negative Symptoms of Schizophrenia

  • Men and women at risk for psychosis experience different emotions and symptoms

  • Biomarkers More Important Than Symptoms When it Comes to Schizophreni

  • Schizophrenia Delusions

  • Hearing Voices

  • Schizophrenia and Substance Abuse

  • Schizophrenia and Hallucinations

  • Managing Symptoms

  • Investigational Drug Shows Promise for Negative Symptoms of Schizophrenia

  • Some Schizophrenia Drugs Can Make Symptoms Worse

  • Mild symptoms of schizophrenia

  • Is that my thought - or did someone put it there? How neural dysfunction is linked to schizophrenia symptons

  • Schizophrenic Tendencies: Precursor To The Illness

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Email: site@toseekmedia.com.

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ScienceDaily - Schizophrenia News 
ScienceDaily - Schizophrenia News 

ScienceDaily features breaking news about the latest scientific discoveries including current medical research on schizophrenia symptoms, medication and more. 

 

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Self Injury Self Help (SISH)
Self Injury Self Help (SISH)

Self Injury Self Help (SISH) is a self help support groups for people who self injure. The original founders of the group wanted to create a safe space to talk about their self harm, and offer and receive support from each other that was non-judgemental and accepting. The groups have run with these core principles ever since, and are one of the few self injury self help groups in the country.

What do we mean by self injury / self harm?

People of all ages and backgrounds do things that are harmful to themselves especially when they are under pressure or in distress.  Self injury is also sometimes known as self harm. For SISH, self harm means that anything that a person views as self injury or self harm counts! Here are some examples:

  • Cutting
  • Burning
  • Biting
  • Thumping self or objects
  • Swallowing objects or substances
  • Overdosing.
  • Not looking after themselves
  • Dangerous driving
  • Getting into fights
  • Staying in relationships that make you feel bad. 

There are many reasons why a person may use self injury. To cope with difficult feelings, memories or situations; to let out anger or distress; to get a sense of control over themselves and their life and many other reasons beside! In the past, members have attended the SISH group who are actively self injuring, or dealing with scars relating to past self injury, or concerned that they are having worrying thoughts that they might hurt themselves in some way. Some people attend because they see other behaviours, such as their use of sex or food, as harmful to themselves. Whatever you are concerned about, SISH is there for you.

 

Organisation

Country: United Kingdom of Great Britain and Northern Ireland

Postal Address: SISH c/o PO Box 3240, Bristol BS2 2EF

Email: sishbristol@gmail.com

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Support or Self-Help Groups Education & Training

Resources

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Simon McCarthy-Jones
Simon McCarthy-Jones

Dr Simon McCarthy-Jones is an Associate Professor in Clinical Psychology and Neuropsychology in the Department of Psychology. He teaches on Trinity’s Bachelor Degree in Medicine, being the Director of the 1st year Behavioural Science course and the 3rd year Psychology and Psychiatry as Applied to Medicine course. His research focuses on three topics:

  • Auditory verbal hallucinations (‘hearing voices’)
  • Child sexual abuse
  • The right to freedom of thought

 

 

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Email: https://www.simonmccarthyjones.com/contact-me/

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Successful Schizophrenia
Successful Schizophrenia

Successful Schizophrenia is a website iaimedto help psychiatry free itself from the delusions that keep it from being an effective medical speciality and to provide proof that thousands of people are right when they say they are NOT mentally ill"

 

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Resources Research Publications & Articles Stories & Speeches Directories Links

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SZGene (SchizophreniaGene)
SZGene (SchizophreniaGene)

SZGene (SchizophreniaGene) is a field Synopsis of Genetic Association Studies in schizophrenia. SZGene is a legacy database that includes the results of candidate gene studies published before 2012. SZGene also provides an overview of all published large-scale and genome-wide association studies in schizophrenia. SZGene maps:

  • Genes
  • Proteins
  • Polymorphism
  • GWAS studies
  • Large-scale association studies
  • Forums
  • Current hypothesis
  • Idea Lab
  • Online Discussions
  • Virtual Conferences
  • Interviews
  • Tech Corner
  • Resources of what we know
  • SchiziophreniaGene
  • Animal Models
  •  Drugs in Trials
  • Research Tools
  • Grants
  • Jobs
  • Conferences
  • Journals
  • Community Calendar
  • General Information
  • Member Directory
  • Researcher Profiles
  • Institutes & Labs

 

 

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The Schizophrenia Home Page
The Schizophrenia Home Page

The Schizophrenia Home Page is a website  devoted to schizophrenia, and to helping the people who are living with it. The website features articles on diagnosis and treatment, as well as many helpful sections on reintegration. Schizophrenia.com hosts several discussion groups, including online support for patients, families, and friends, as well as separate forums for talking about medications and treatment.

 

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The Schizophrenia Library NeuRA
The Schizophrenia Library NeuRA

The Schizophrenia Library provides reliable and up to date information from systematic reviews on around 460 topics relating to schizophrenia. The topics cover symptoms, treatments, diagnosis, risk factors, outcomes, co-occurring ‘comorbid’ conditions, epidemiology (population perspective), and the physical features of schizophrenia.

  • Assessment & Diagnosis
  • Signs & Symptoms
  • Treatments
  • Risk factors & Antecedents
  • Illness Course & Outcomes
  • Insight For Families
  • Physical Features
  • Co-occurring Conditions
  • Epidemiology
  • FAQs
1st Generation Anti-Psychotics (Typical Anti-Psychotics)
1st Generation Anti-Psychotics (Typical Anti-Psychotics)

First generation ‘typical’ antipsychotics are an older class of antipsychotic than second generation ‘atypical’ antipsychotics. They are used primarily to treat positive symptoms including the experiences of perceptual abnormalities (hallucinations) and fixed, false, irrational beliefs (delusions). These include:

  • Benperidol

  • Bromperidol

  • Chlorpromazine

  • Droperidol

  • Flupentixol

  • Fluphenazine

  • Fluspirilene

  • Haloperidol

  • Levomepromazine

  • Loxapine

  • Metiapine

  • Molindone

  • Penfluridol

  • Perazine

  • Perphenazine

  • Perazine

  • Perphenazine

  • Pimozide

  • Piperacetazine

  • Pipotiazine

  • Sulpiride

  • Thioridazine

  • Trifluoperazine

  • Zuclopenthixol

  • Side effects

  • All antipsychotics versus placebo

  • First versus second generation

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2nd Generation Anti-Psychotics (Atypical Anti-Psychotics)
2nd Generation Anti-Psychotics (Atypical Anti-Psychotics)

Second generation antipsychotics (sometimes referred to as ‘atypical’ antipsychotics) are a newer class of antipsychotic medication than first generation ‘typical’ antipsychotics. Second generation antipsychotics are effective for the positive symptoms of schizophrenia. It is sometimes claimed that they are more effective than first generation antipsychotics in treating the negative symptoms of schizophrenia, although the evidence for this is weak. Negative symptoms include a lack of ordinary mental activities such as emotional expression, social engagement, thinking and motivation, whereas positive symptoms include the experiences of perceptual abnormalities (hallucinations) and fixed, false, irrational beliefs (delusions).

  • Amisulpride

  • Aripiprazole

  • Asenapine

  • Blonanserin

  • Brexpiprazole

  • Cariprazine

  • Carpipramine

  • Clocapramine

  • Clotiapine

  • Clozapine

  • Iloperidone

  • Lurasidone

  • Mosapramine

  • Olanzapine

  • Paliperidone

  • Perospirone

  • Quetiapine

  • Remoxipride

  • Risperidone

  • Sertindole

  • Ziprasidone

  • Zotepine

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Adjunctive Treatments for Schizophrenia
Adjunctive Treatments for Schizophrenia

There are a number of supplementary (or adjunctive) treatment that are administered in conjunction with a patient’s ongoing antipsychotic therapy. These include:

  • Adenosine modulates (particularly dipyridamole and propentofylline) may improve symptoms, particularly positive symptoms, in people with schizophrenia.
  • Amphetamines: single-dose dexamfetamine or methylphenidate increases severity or frequency of positive symptoms, particularly in patients who are not in remission.
  • Analeptics (such as modafinil) have been suggested as potential adjunctive treatments for schizophrenia. Modafinal is a wake-promoting drug (mechanisms of action unknown) which is thought to help with the sedation side-effects of antipsychotics. 
  • Anti-inflammatory: growing evidence suggests that inflammatory processes may contribute to the development of schizophrenia. This suggests a potential role for anti-inflammatory medications, such as non-steroidal agents (e.g., aspirin) which may be potentially useful therapeutic strategies, particularly in combination with ongoing antipsychotic medication.

  • Anticholinergics block the action of the neurotransmitter acetylcholine. Anticholinergic medications may have some utility for the treatment of side effects of antipsychotic medications, including movement disorders like akathisia (a type of restlessness, a common side effect of many neuroleptics), as well as excessive salivation. 

  • Anticonvulsant medications influence the actions of neurotransmitters including glutamate and GABA, leading to a decrease in brain cell (neuron) excitability. They may be prescribed as an immediate adjunct to antipsychotic medication in order to treat acute symptoms of psychosis, such as aggressive behaviour. They may also be used as part of an ongoing treatment regime in order to supplement antipsychotic effects or combat side effects like movement disorders. Anticonvulsant medications assessed in this topic primarily include valproate, carbamazepine, and lamotrigine.

  • Anticraving medications (such as naltrexone) that aim to reduce craving for and use of substances may improve substance dependence in people with schizophrenia.

  • Antidepressants: have been proposed as an additional therapy to standard antipsychotic treatments, in an attempt to improve functional outcomes and treat symptoms that are not addressed by the antipsychotic medication alone. Antidepressant medications have been studied as treatments for the symptoms of schizophrenia, particularly negative symptoms, as well as for treating people with co-occurring schizophrenia and depression.

  • Benzodiazepines may be implemented as an adjunct to antipsychotic medication in order to treat acute symptoms of psychosis such as agitation, aggression, irritability, or anxiety. They may also be used to treat side effects of antipsychotic medications such as movement disorders including tardive dyskinesia, however they are associated with their own side effects and are associated with well-established patterns of tolerance and dependence, so they are prescribed with caution.

  • Beta blockers can be prescribed in addition to standard antipsychotic regimes in order to target some side effects of these medications, including extrapyramidal symptoms such as akathisia (a type of restlessness, a common and early-onset side effect of many neuroleptics). Beta blockers have also been used to reduce the physical symptoms of anxiety in people with schizophrenia (for example, pounding heart, clammy hands, sweating), and have also been suggested to reduce aggression.

  • Calcium channel blockers are prescribed with extreme caution due to their potential for extreme side effects, and the dopamine-blocking actions that may interfere or interact with neuroleptic medications.

  • Cannabinoids

  • Catecholamines: L-DOPA improve overall symptom severity and may benefit tardive dyskinesia.

  • Cholinergic medications have been prescribed for tardive dyskinesia, which is a common side effect of antipsychotics, involving repetitive, involuntary movements most commonly occurring around the mouth and face. 

  • Cholinesterase inhibitors (ChEI) (or anticholinesterase) have been proposed as an additional therapy to standard antipsychotic treatments in an attempt to improve functional outcomes and treat symptoms that are not addressed by the antipsychotic medication alone. 

  • Erythropoietin

  • Essential fatty acids: people with schizophrenia have shown to have lower levels of these essential compounds and their products,including omega-3 products docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), its esther, ethyl-eicosapentaenoic acid (E-EPA), omega-6 product arachidonic acid (AA), and their metabolites including prostaglandins (PGE).

  • GABA (gamma-aminobutyric acid) is a common neurotransmitter in the brain, and GABA-ergic neurons are thought to interact with antipsychotic medications, contributing to side effects such as tardive dyskinesia. GABA-acting medications (such as baclofen, progabide, or sodium valproate) may contribute to increasing the activity of GABA neurons, potentially leading to reduced medication side effects. 

  • GHB

  • Glutamate receptor modulators: have been suggested as an adjunctive therapy to standard antipsychotic treatments, when individuals have sub-optimal responses to treatment. The glutamate receptor modulators that have been trialed in schizophrenia are predominantly amino acids, and act on several different aspects of the glutamatergic neurotransmission system. Agents include glycine, D-serine, D-cycloserine, D-alanine, CX516, sarcosine, N-acetyl cysteine, and memantine. These agents have been studied for efficacy in improving symptom severity and cognitive function.

  • Mood stabilisers have been proposed as an adjunctive therapy to standard antipsychotic treatments when individuals have sub-optimal responses to treatment. Mood stabilisers may be implemented as an immediate therapy for acute symptoms of psychosis, but they may also be used as part of an ongoing treatment regime. Mood stabiliser medications assessed in this topic include lithium as well as anticonvulsant medications (valproate, carbamazepine, and lamotrigine).

  • Nicotine

  • Oestrogen is a hormone that has been proposed to confer a protective effect for schizophrenia.  This protective effect may mean that pre-menopausal women who develop schizophrenia may experience a less severe illness than males. Oestrogens are not used routinely for people with schizophrenia; however some studies have trialed the use of oestrogen as an additional, adjunctive treatment to standard antipsychotic treatment.

  • Oxytocin is a neuromodulatory neuropeptide that is important for the correct processing of emotional stimuli in a social context. It has been proposed that difficulties in social cognition in schiozphrenia and other disorders such as autism, are underpinned by disruption in the dopaminergic/oxytonergic circuitry linked to socio-emotional processing. Oxytocin has been linked to prosocial behaviours in some studies, but not in others. So, oxytocin effects may be moderated by features of the social environment or individual differences.

  • Promethazine medications are a type of sedative, in the class of antihistamine drugs. One widely known commercial promethazine is Phenergan. They work on the central nervous system, resulting in a decrease in brain cell activity. Promethazine has been used in combination with antipsychotics in situations where benzodiazepines may not be used in order to evoke sedative effects.

  • Serotonin Modulators: atypical antipsychotics are thought to have some affinity for serotonin 5-HT receptors (e.g. clozapine, quetiapine and olanzapine among others) suggesting a potential for the use of serotonin-specific medications in the treatment of schizophrenia.

  • Sodium nitroprusside

  • Statins are effective cholesterol lowering agents and are used to prevent cardiovascular disease improving symptoms of schizophrenia when given in conjunction with antipsychotics.

  • Testosterone is a hormone that has shown to be reduced in people with schizophrenia. Although not used routinely as a therapy for schizophrenia, some studies have trialed the use of testosterone as an additional, adjunctive treatment to standard antipsychotic treatments.

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Antecedents of Schizophrenia
Antecedents of Schizophrenia

Antecedents are physical and cognitive alterations observed in people prior to the onset of schizophrenia, usually in childhood and adolescence, and may be early indicators of illness progression. They are still being investigated, but may include motor and cognitive dysfunction, speech and language impediments, behavioural problems and psychopathology such as anxiety, delusions and hallucinations.

  • Attention dysfunction

  • Autonomic nervous system anomalies

  • Behavioural disturbances and psychopathology

  • Dermatoglyphic anomalies

  • Eye tracking anomalies

  • Face emotion processing anomalies

  • Height and body mass index

  • IQ and academic performance

  • Mild physical anomalies

  • Motor dysfunction

  • Olfactory identification deficits

  • Sleep disturbance

  • Speech and hearing deficits

  • Stress responsivity anomalies

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Assessment & Diagnosis of Schizophrenia
Assessment & Diagnosis of Schizophrenia

A diagnosis of schizophrenia is not a simple one, with symptoms varying across individuals. This category contains information about diagnostic tools for schizophrenia and related disorders, and early detection tools for identifying those at risk of a first episode of psychosis.

  • Outcome Assessment Tools

  • Early Detection

  • First-Episode Psychosis

  • High-Risk Groups

  • Treatments for High-Risk Groups

  • Duration of Untreated Psychosis and Outcomes

  • Duration of Untreated Psychosis

  • Cognition in High-Risk Groups

  • Treatments for Cognitive Symptoms

  • Schizoaffective Disorder

  • Schizophrenia

  • Schizophreniform Disorder

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Associated Treatment for Schizophrenia
Associated Treatment for Schizophrenia
  • Treatments for constipation: adjunct medications prescribed to treat side effects such as constipation may contribute to increasing adherence to antipsychotics which can reduce the risk of psychotic relapse.

  • Treatments for hyperprolactinaemia: one potential side effect of antipsychotic use is hyperprolactinaemia, which can disrupt sex hormones and the production and flow of breast milk, and can cause infertility and erectile dysfunction in men. Hyperprolactinaemia is caused by blocking of the D2 dopamine receptor at the anterior lobe of the pituitary gland, resulting in high prolactin levels. As different antipsychotics have different actions, they also differ in the degree to which they affect prolactin levels.

  • Treatments for hypersalivation: antipsychotic medications (such as clozapine and olanzapine among others) may induce excessive (hyper) salivation, which can be uncomfortable and embarrassing as well as increasing the risk of aspiration pneumonia. Various pharmacological approaches have been used to try and alleviate this problem. Adjunctive medications prescribed to treat such side effects may contribute to increasing adherence to antipsychotic medications, which reduces the risk of psychotic relapse.

  • Treatments for movement disorders: the antipsychotic promethazine and pyridoxal 5 phosphate (vitamin B6), the anxiolytic buspirone, the cognitive enhancer/stimulant pemoline, and the alkaloids dihydrogenated ergot alkaloid and L-Stepholidine, GABA-acting medications, branched-chain amino acids, enzyme VMAT2 inhibitors, ginkgo biloba, and the antiepileptic levetiracetam, the antidepressant isocarboxazid over the anticholinergic procyclidine all help reduce tardive dyskinesia. There were no significant benefits for tardive dyskinesia of ceruletide, vitamin E, cholinergic medications, noradrenergic or dopaminergic medications, benzodiazepines, evening primrose oil, lithium, oestrogen, the antidepressants selegiline and ritanserin, melatonin, the antihistamine cyproheptadine, the alkaloid papaverine, the cognitive enhancer piracetam, eicosapentaenoic acid derivative, and the antiepileptic levetiracetam. 

  • Treatments for sexual dysfunction: sildenafil may improve sexual functioning in males with schizophrenia.

  • Treatments for sleep disturbance

  • Treatments for smoking cessation: heavy cigarette use may contribute to the increased mortality and reduced life expectancy reported within the schizophrenia population.

  • Treatments for weight gain

  • Herbal medicines

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Biochemical Changes in Schizophrenia
Biochemical Changes in Schizophrenia

Biochemical changes include the research into changes in biochemical levels in people with schizophrenia, which indicate markers for the disorder and can provide insights into improved drug treatments.

  • Brain pH and lactate

  • cAMP

  • Cholesterol

  • Dopamine is a neurotransmitter that is important for emotional and cognitive processing in the brain, particularly rewarding and pleasurable stimuli or experiences. Alterations of the dopamine system have been suggested in schizophrenia. This may be assessed as changes in levels of dopamine or its metabolites, or as changes in levels or activity of the mechanical components of the dopamine system, such as the receptors that receive dopamine, or the transporters that remove it.

  • GABA (gamma-aminobutyric acid) is the most important inhibitor of neurotransmitters in the central nervous system and is often dysfunctional in people with mood disorders that has also been investigated in people with schizophrenia. GABA can be measured via peripheral levels in plasma, via central levels in cerebrospinal fluid, and in brain regions using magnetic resonance spectroscopy (MRS). Possible GABA dysfunction has led to interest in GABA-acting medications as possible adjunctive treatments for schizophrenia (such as baclofen, progabide, and sodium valproate).

  • Homocysteine

  • Hormonal Changes

  • Hypothalamic-pituitary-adrenal axis (HPA)

  • Infectious Agents

  • Lipids

  • Inflammatory and immunological change

  • Melatonin

  • Neurometabolites

  • Neuropeptides

  • Nitric Oxide (NO): disturbances in NO formation or release could interfere with the known functions of NO activity (including neural maturation and synapse formation) could have relevance for possible neurodevelopmental aetiology of schizophrenia.

  • NMDA receptor function: there may be changes in levels of glutamate and its metabolites and changes in levels or activity of mechanical components of the NMDA receptor system (such as the receptors that ‘receive’ glutamate or the transporters that ‘remove’ it) in schizophrenia.

  • Oxidative stress: there is decreases in catalase and superoxide dismutase in red blood cells, and decreases in nitrate and uric acid in plasma in people with first-episode psychosis.

  • S100 proteins: there is a potential susceptibility of S100 gene in schizophrenia.

  • Serotonin is a neurotransmitter whose dysregulation may underlie the negative symptoms and high rates of depression seen in people with schizophrenia. Selective serotonin reuptake inhibitors have been found to be effective in treating the negative symptoms of the disorder with acute tryptophan depletion (a dietary manipulation that lowers brain serotonin (5-HT) synthesis) being shown to worsen negative symptoms.

  • Synaptic Proteins

  • Translocator protein

  • Vitamin B

  • Vitamin D

  • Zinc: reduced zinc levels in people with schizophrenia compared to people without schizophrenia, particularly in patients who were newly diagnosed and drug-naive.

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Brain Structures & Schizophrenia
Brain Structures & Schizophrenia

There are numerous changes of brain structure in people with schizophrenia, particular in the various regiuons of the brain

  • Brain weight
  • Amygdala 

  • The arcuate fasciculus 

  • The basal ganglia

  • Cerebellum

  • Cingulate cortex

  • Claustrum

  • Corpus callosum

  • Default mode network

  • Frontal Lobe

  • Hippocampus

  • Insular Cortex

  • Occipital Lope

  • Pareital Lobe

  • Temporal Lobe

  • Thalamus

  • Ventricular System

  • Wholve Brain Volume

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Cognitive Signs & Symptoms of Schizophrenia
Cognitive Signs & Symptoms of Schizophrenia

Cognition signs and symptoms include a lack of function mental actions or processes such as attention, memory, planning, problem solving, and social cognition. Research into cognition in people with schizophrenia has found anomalies across a range of thought processes, which interfere with the individual’s ability to function. 

  • Attention
  • Cognition in high-risk groups

  • Cognition in schizophrenia and bipolar disorder

  • Cognitive functioning related to symptoms

  • Decision Making

  • Defeatist performance beliefs are over-generalised negative thoughts about one’s ability to successfully perform goal-directed behaviour. This prevents the initiation of and engagement in social and employment opportunities and therefore is considered a possible contributing factor to negative symptoms and poor functional outcomes.

  • Episodic future thinking refers to thought processes that contribute to the mental construction, imagination or simulation of possible future events. Episodic future thinking plays a role in planning, problem-solving, coping, regulating emotional states and goal-motivated behaviour.

  • Executive functions are a group of cognitive processes involving control, mental flexibility, planning, inhibition, decision-making, initiation, abstraction, self-monitoring and pursuit of goals. Any impairment in executive functioning can also reflect impairments in other cognitive functions such as processing speed, attention, and memory. 

  • Impulsivity is a predisposition towards unplanned reactions to internal or external stimuli, without regard to the consequences, which is a major feature in a variety of psychiatric disorders.

  • Information processing involves a number of cognitive functions (including perception, attention, memory, decision making and the speed at which these cognitive functions are executed with impairments in information processing reflecting impairments in these other cognitive domains.

  • Insight is defined as the awareness of having a mental disorder including an understanding of the social consequences associated with the disorder; the need for treatment; the effects of medication; an awareness of the implications; and awareness of the signs and symptoms of the disorder. Insight is clinically important as it is linked to non-adherence of treatment, as patients who lack insight may not believe they have a psychotic illness and therefore do not believe they need medication.

  • IQ: moderate to high quality evidence finds a large effect of lower IQ in people with schizophrenia, including people with first-episode, youth-onset, or late-onset schizophrenia, with late-onset samples showing the greatest impairment.

  • Language may be altered in people with schizophrenia and may present in the form of disorganised speech. 

  • Learning: people with schizophrenia have poorer verbal learning, verbal memory, verbal paired associate learning and verbal recognition. Learning is the ability to acquire, or change, existing knowledge, behaviours or skills.

  • Memory: people with schizophrrenia have poorer short-term, long-term, working, episodic, prospective, and memory binding in people with schizophrenia. Memory involves encoding, storage and retrieval of information.

  • Metacognition refers to ‘thinking about thinking’ and involves active control over the cognitive processes engaged in thinking and acquiring knowledge or learning. Negative beliefs about thoughts (e.g. uncontrollability and dangerousness) and more cognitive confidence (confidence in one’s memory and attentional capabilities) have been absorbed in people with psychotic disorders.

  • Psychomotor ability refers to a wide range of actions involving physical movement with poor psychomotor ability in people with schizophrenia, including people with first-episode schizophrenia, or early onset schizophrenia.

  • Reasoning Ability refers to the ability to logically gather information to form conclusions and solve problems. People with schizophrenia may show impaired reasoning, with bias in the way they gather information, interpret events and develop beliefs. 

  • Rigidity is an inability to change mental or behavioural sets when required (i.e. behavioural, cognitive or attitudinal) and plays a large affect in people with disabilities. 

  • Social Cognition: people with schizophrenia often have impaired social perception, emotion perception, emotion processing, impaired social knowledge, biological motion processing, and empathetic abilities.

  • Time perception involves the capacity to accurately process temporal information that is embedded in relevant events with the ability to perceive, remember, and organise behaviour in periods ranging from seconds to minutes mediates functions, from basic motor coordination to decision making in people with schizophrenia.

  • Tone Perception: low-level sensory functioning may be impaired in people with schizophrenia and may contribute to higher-order cognitive and social impairments. Tone perception involves pitch discrimination, 

  • Visuospatial ability refers to a person’s capacity to identify visual and spatial relationships among objects with poor global visuospatial ability often appearing in people with schizophrenia

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Comorbidities with Shizophrenia
Comorbidities with Shizophrenia
  • Anxiety

  • ADHD

  • Autism
  • Depression

  • Dissociative Disorders

  • Intellectual Disability

  • Personality Disorders

  • Polydipsia

  • PTSD

  • Substance Use

  • Drug & Alcohol Use

  • Smoking

  • Auditory system dysfunction: people with schizophrenia may show increased rates of unrelated co-occurring dysfunction of the auditory system or structural abnormalities of the ear canal.

  • Autoimmune diseases: people with schizophrenia may show increased rates of autoimmune diseases are caused by an overactive immune system.

  • Blood disorders: people with schizophrenia may show increased rates of co-occurring conditions disorders of the blood such as leukocytosis (excess leukocytes), hypokalemia (reduced potassium), and neutropenia (low neutrophil levels).

  • Cancer

  • Cerebrovascular Disorder

  • Dementia

  • Diabetes

  • Digestive Disorders: people with schizophrenia may show increased rates of co-occurring conditions, including appendicitis, gastric ulcers, irritable bowel syndrome, or celiac disease.

  • Epilepsy

  • Infectious Disabilities

  • Metabolic Syndromes

  • Musculoskeletal and connective tissues

  • Obesity: people with a severe mental illness are at increased risk of obesity, which may be due to genetic and/or socio-economic factors, lifestyle choices, or metabolic effects of psychotropic medications. 

  • Peripheral vascular disease

  • Polycistic ovary syndrome

  • Postoperative complications

  • Reproductive and urological disorders

  • Respiratory system dysfunction

  • Skin Disorders

  • Sleep Apnoea

  • Thyroid Disorders

  • Underweight

  • Visual Impairment

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Diagnostic Testing in Schizophrenia
Diagnostic Testing in Schizophrenia
  • Electroencephalography (EEG) uses electrodes on the scalp to measure electrical activity from the brain. Quantitative spectral EEG investigates several waveforms, and so the activity can be measured, but EEG also gives rise to event related potentials (ERP), which measure the EEG activity directly evoked by a stimulus, often using cognitive or perceptual stimuli.
  • Functional magnetic resonance imaging (fMRI) is used to determine functional activation of brain regions when an individual performs tasks (or rests) inside an MRI scanner. Most commonly fMRI studies use visual, auditory, motor or sensory stimuli to evoke neural responses in the brain. Recent fMRI studies also examine activity of the brain at rest. Changes in blood flow are interpreted to represent brain activation (or deactivation) associated with a particular brain state (i.e, while performing a particular activity, or while the brain is at rest). Functional activity has been investigated in people with schizophrenia compared to people without schizophrenia to identify regions of increased or decreased brain function on the basis of blood flow.
  • Magnetoencephalography (MEG) uses a helmet-shaped device containing MEG sensors (gradiometers) to noninvasively measure the magnetic fields produced by neural activity of the brain. MEG is able to localise the source of neural activity to particular brain regions, represented as positive and negative charges (dipoles), with greater accuracy than EEG, which is a measure of the electrical fields produced by neural activity. MEG can be used to measure continuous resting-state brain activity (spontaneous MEG), but also to assess event-related changes in brain activity. 

  • Transcranial magnetic stimulation (TMS) is a non-invasive method that assesses inhibitory and excitatory mechanisms in the brain. Inhibitory processes include the cortical silent period, which is measured from the motor evoked potential onset to the return of electromyography.

  • Computed tomography (CT): is a method for visualising the structural organisation of the brain using the attenuation of X-rays to generate image contrast. Tissues in regions of interest are highlighted based on their X-ray absorption properties, as dense tissues attenuate X-rays more than soft tissues, and air attenuates the least. Three-dimensional images are generated from a series of two-dimension X-ray images taken around a single axis of rotation.

  • Optical coherence tomography (OCT):  is an imaging technology that assesses the thickness of the peripapillary retinal nerve fibre layer, macular thickness, and volume. It has been used to assess neurologic diseases such as multiple sclerosis, Alzheimer’s disease, and Parkinson’s disease, and more recently, schizophrenia.

  • Diffusion tensor imaging (DTI): DTI is a specialised imaging technique that uses MRI technology to investigate the movement of water within tissues of interest. By applying a magnetic field, the movement (“diffusivity”) of water molecules can be visualised in vivo. The diffusion of water is influenced by the cellular structure of the surrounding tissues, and measures such as fractional anisotropy (FA) were derived as an approximate measurement for the freedom of movement. In areas of high structural coherence such as white matter, FA is highest, indicating that water is moving in relatively fixed directions. It is lower in grey matter, and close to zero in cerebrospinal fluid, indicating that water is moving freely. Consequently, changes in FA values are interpreted to be representing alterations in the structural integrity of the regional white matter.

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Early Detection of Schizophrenia
Early Detection of Schizophrenia

Early detection refers to the correct identification of individuals who are at high risk of developing schizophrenia, with an emphasis on the development of frank psychosis. Several assessment tools have been constructed to effectively identify such individuals. Sensitivity of an assessment tool refers to the proportion of people who develop psychosis that were previously identified by the assessment tool as being at high risk. Specificity is the proportion of people who do not develop psychosis that were previously identified as not being at high risk. Assessment tools therefore aim to have both high sensitivity and high specificity. Generally, there are two approaches that dictate the characteristics used as markers for detection.

  • The ultra-high risk approach focuses on a triad of at-risk mental states defined as:
  1. Having a family history of psychosis plus non-specific symptoms and a recent decline in functioning
  2. Showing recent onset of attenuated psychotic symptoms with a decline in functioning
  3. Symptoms must be brief, intermittent and limited
  • Huber’s Basic Symptoms: focus in a detailed way of describing subjective disturbances, and may be an earlier indicator of risk than the first approach.

the mean rate of transition to psychosis in those assessed as being at clinical high risk for psychosis is around 16% by 2 years and 29% by 3 years. In people assessed as being at clinical high risk of obsessive-compulsive disorder are at higher risk of psychosis than people assessed as being at clinical high risk of bipolar disorder, which in turn has higher risk of psychosis than people assessed as being at high risk of depression. However, the rate of transition to psychosis are only one third the rate of transition to non-psychotic disorders in people at assessed as being at clinical high risk for non-psychotic disorders.

In children and adolescents assessed as being at clinical high risk of psychosis, transition rates were between 17% and 20% by 1 year follow-up and between 7% and 21% by 2 year follow-up. 36% of children and adolescents recovered from their clinical high risk status by 6-year follow-up, and 40% continued to meet clinical high risk criteria without transition to psychosis.

Studies with older samples reported higher transition rates than studies with younger samples, and more recent publications reported lower transition rates than older publications. Studies using the basic symptoms approach reported higher transition rates than studies using the ultra-high risk approach. Studies of people receiving psychosocial treatments (e.g. cognitive behavioral therapy) reported lower transition rates than studies of people receiving standard care (e.g. case management). Studies of people on antipsychotics also reported lower transition rates than studies of people not on antipsychotics. Evidence suggests:

  • Instruments based on ultra-high risk criteria have good sensitivity and moderate specificity. Moderate to low quality evidence also suggests the BSABS scale as good sensitivity and moderate specificity. This indicates validated instuments are generally good at correctly identifying individuals who do develop psychosis, but not as good at identifying individuals who do not develop psychosis.
  • The model with the best predictive value (86%) for transition to psychosis was a clinical model including:
  1. Odd beliefs
  2. Marked impairment in role functioning
  3. Blunted affect
  4. Auditory hallucinations and
  5. Anhedonia/asociality.
  • A biological model using grey matter volume, and a neurocognitive model using IQ, verbal memory, executive functioning, attention, processing speed, and speech perception, both had positive predictive values of 83%.
  • An environmental model with a positive predictive value of 63% involved urbanicity, social-sexual aspects, and social-personal adjustment.
  • The best combination model had a positive predictive value of 82% and involved: 
  1. Disorganised communication
  2. Suspiciousness
  3. Verbal memory deficit and
  4. Decline in social functioning.

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Epidemiology of Schizophrenia
Epidemiology of Schizophrenia

A population perspective provides epidemiological estimations of the prevalence and incidence of schizophrenia in different populations and regions worldwide. This topic considers the history and burden of schizophrenia, and the implications of mental health laws and policies on the treatment and management of the disorder.

  • Burden of Schizophrenia
  • History of Schizophrenia
  • Schizophrenia Policy & Law
  • Overall Incidence of Schizophrenia: the worldwide incidence of schizophrenia and how it varies according to place.
  • Spatial Incidence Variation of Schizophrenia
  • Worldwide Incidence of Schizophrenia
  • Prevalence of Schizophrenia
  • Spatial Prevalence of Schizophrenia
  • Worldwide Prevalence of Schizophrenia

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Families & Schizophrenia
Families & Schizophrenia

Schizophrenia has a large genetic component and as such, families of people with schizophrenia may also be affected by the disorder. Schizophrenia has an impact on the family unit, and also cognitive and physiological alterations in relatives.

  • Cognition in families related to schizophrenia: cognitive deficits have been reported in people with schizophrenia including deficits in memory, attention and executive functioning are most commonly reported, with lesser degree of dysfunction in perceptual and language processes. Cognitive deficits are present early in the course of the disorder and are stable over time, and may be heritable. First-degree relatives of people with schizophrenia may show attenuated signs of cognitive deficits.

  • The collection of information relating to a person’s family history of mental illness can be a valuable tool for diagnosing and understanding their current mental state, in both clinical and research settings, where it may not be feasible to interview the family members themselves. A patient can usually correctly identify a particular family member with schizophrenia, if one exists.

  • Familial coaggregation is the rate of related disorders found in a family. Many studies have suggested a fundamental association between schizophrenia and bipolar disorder. 

  • Family relationships: several familial traits have been associated with increased risk for schizophrenia including familial high expressed emotion (hostility, emotional over-involvement, and critical comments); negative parental affective style (guilt induction, over-intrusiveness, and personal criticism); and communication deviance (lack of clarity in communication). People with schizophrenia may have had poor relationships with parents during childhood, with increased family instability, high communication deviance, negative emotions, and poor self-concept.

  • Impact on families: a diagnosis of schizophrenia can have a large impact not only on the affected individuals, but also on the people closest to them. This topic considers the impact of schizophrenia on family members, and on the family as a unit. Sometimes the family of a person with schizophrenia may experience different types of burden, particularly during acute phases of the illness. 

  • Physical anomalies in first-degree relatives: relatives of people with schizophrenia may show attenuated signs of the illness (such as physical features that are commonly identified with the disorder). Identifying these signs can help determine how genetics may contribute to the risk of schizophrenia.

  • Psychopathology in first-degree relatives

  • Sibship is a medical term meaning a group of individuals born of the same parents. Factors associated with sibship include birth order, number of siblings or number of births in the family, and inter-birth interval periods. It is not known how these factors may be associated with risk for schizophrenia. There is increased risk of schizophrenia in people who had one, four or five births in their family, or in children born less than 18 months before or after their closest sibling. First birth order may be associated with a reduced risk for schizophrenia.

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Frequently Asked Questions About Schizophrenia
Frequently Asked Questions About Schizophrenia
  • What is schizophrenia and how is it diagnosed?

  • Which risk factors are associated with schizophrenia?

  • Which treatments are most effective?

  • Will family members be affected?

  • Would my treatment change if I also have another disorder?

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Functional Changes in Schizophrenia
Functional Changes in Schizophrenia

Brain functional alterations are investigated by using imaging technologies such as functional magnetic resonance imaging and electroencephalogram, and by assessing physical anomalies such as changes in chemical levels and bodily functions.

  • Body functioning: changes in body functioning in people with schizophrenia, including movement and sleep disturbances.
  • Biochemical changes: changes in biochemical levels in people with schizophrenia that may indicate markers for the disorder and can provide insights into improved drug treatments.
  • Cerebral blood flow and metabolism: functional changes in the way the brains of people with schizophrenia are supplied with blood, and how nutrients are provided to cells.
  • Electrophysiology: voltage changes or electric current in brain cells and tissue of people with schizophrenia.
  • Brain structure: alterations in the brain structure of people with schizophrenia
  • Bodily features: structural anomalies in bodily features in people with schizophrenia.
  • Brain Regions: changes according to specific regions of the brain.

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Non-Pharmaceutical Physical Treatments for Schizophrenia
Non-Pharmaceutical Physical Treatments for Schizophrenia

Non-pharmaceutical physical treatments for schizophrenia include:

  • Acupuncture
  • Biofeedback is a technique in which information about the person’s body is fed back to the person so that they may be trained to alter the body’s conditions.
  • Electroconvulsive therapy (ECT) is a seizure is electrically induced after the patient has been given a short-acting anaesthetic and is asleep.

  • Exercise Therapy

  • Transcranial Direct Current Stimulation (tDCS) is a non-invasive form of brain stimulation similar to transcranial magnetic stimulation, but instead of using magnets, it uses a low-intensity, constant current applied through scalp electrodes.

  • Transcranial Magnetic Stimulation (TMS) uses an electromagnetic coil placed over the scalp to stimulate the nerve cells beneath it. In general, low frequency stimulation reduces nerve cell activity and high frequency stimulation increases nerve cell activity. Repetitive TMS (rTMS) has been tested as a possible treatment for schizophrenia.

  • Vagus Nerve Stimulation (VNS) provides indirect modulation of brain network activity through the stimulation of cranial nerves. Invasive VNS involves surgical implantation of a small pulse generator under the skin which is programmed to deliver long-lasting, intermittent electrical stimulation of the vagus nerve. Non-invasive stimulation involves attaching a stimulator to the outer ear close to the ear canal, which delivers electrical impulses through the skin to the vagus nerve.

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Physical Features of Schizophrenia
Physical Features of Schizophrenia

People with schizophrenia usually have physical alterations to their central nervous system including functional and structural changes.

  • Cortical release signs

  • Movement Disorders

  • Neurological Soft Signs

  • Olfactory Functioning

  • Pain Sensitivity

  • Sleep Disturbance

  • Temperature Regulation

  • Biochemical Changes

  • Cerebral blood flow and metabolism

  • Eye Movement Dysfunction

  • Dermatoglyphics

  • Minor Physical Anomolies

  • Morphometrics

  • Telomere length

  • Mismatch negativity (MMN) is an auditory event-related potential that is generated when a stimulus feature deviates from the regularity of previous auditory stimuli. This deviance can be a simple physical characteristic, such as tone duration, intensity, frequency or location; or more abstract presentation characteristics, such as a lower tone in a series of ascending tones. In this way, MMN generation relies on the creation of an auditory (echoic) memory trace for the preceding tones, in order to identify the subsequent deviance. MMN is thought to be an automatic, pre-attentional process and functions as an index of auditory discrimination and echoic memory integrity. MMN is observed as the difference in ERP wave response to the standard stimuli and the deviant stimulus. Larger differences between standard and deviant stimuli and lower probability of deviant occurrence are both associated with larger MMN amplitude.

  • N100

  • N170

  • N250

  • N400

  • P100

  • P200

  • P300

  • P50

  • Prepulse inhibition

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Risk Factors of Schizophrenia
Risk Factors of Schizophrenia

Schizophrenia is a complex disorder and has been associated with many causative factors. With a heritability estimate around 80%, schizophrenia has a strong genetic component and this is reflected in the large number of genes that have been associated with the disorder. At present, the library does not include information on specific genes, but does provide general genetic information, information on family heritability, and the environmental risk factors that have been associated with the disorder. We also include information on the antecedents of schizophrenia, which are potentially very early signs of the disorder. Non-genetic risk factors include various prenatal and perinatal stressors, infectious agents, childhood and adulthood trauma and substance use. The strength of association between non-genetic factors and the subsequent development of schizophrenia is still largely unknown and the interaction effects between genetic and non-genetic factors vary from person to person.

  • Genetic Risk Factors
  • Genetic & Non-Genetic Risk
  • Genetics
  • Adult Life Events
  • Childhood Adversity
  • Congenital rubella syndrome
  • Environmental Toxins
  • Ethnicity
  • Family Relationships
  • Famine
  • Infectious Agents
  • Latitude, climate and winter birth
  • Marital status
  • Maternal diet and body mass index
  • Maternal illness during pregnancy
  • Migration
  • Obstetric complications
  • Parental age at birth
  • Parental education
  • Parental psychological factors
  • Sex differences
  • Sibship
  • Social capital
  • Socioeconomic Status
  • Substance Use
  • Traumatic Brain Injury
  • Urban Environment

 

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Schizophrenia Lifecourse
Schizophrenia Lifecourse
  • Age of Onset
  • Childhood and early-onset schizophrenia
  • Duration of untreated psychosis
  • First-episode psychosis
  • Late Onset Schizophrenia
  • Mortality
  • Remission & Recovery
  • Psychotic Relapse

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Schizophrenia Outcomes
Schizophrenia Outcomes

The course and outcomes of disorders vary widely between individuals including chronic schizophrenia, early and late-onset schizophrenia, and first-episode psychosis. Outcomes affecting day to day life include quality of life, relationships, culture, employment, homelessness, violence and self-harm, and recovery and relapse.

  • Absconding
  • Creativity
  • Criminal offending, aggression and violence
  • Criminal victimisation
  • Cultural differences
  • Diet
  • Drug & Alcohol Use
  • Electronic device use
  • Employment
  • Functional Outcomes
  • Homelessness
  • Hope
  • Loneliness
  • Mortality
  • Relationships
  • Parenthood
  • Pathways to Care
  • Physical Activity
  • Physical health monitoring
  • Quality of Life
  • Religosity
  • Sex Differences
  • Smoking
  • Stigma and attitudes towards mental health
  • Suicide and self-harm
  • Treatment Adherence

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Signs & Symptoms of Schizophrenia
Signs & Symptoms of Schizophrenia
  • Positive symptoms are a well-documented feature of schizophrenia and are arguably the most recognisable and conspicuous symptoms. Positive symptoms include hallucinations and delusions. The severity of positive symptoms can significantly affect a person’s day-to-day function, quality of life, and may also be associated with impaired cognitive ability. Positive symptoms have been shown to be more responsive to antipsychotic treatment than other symptom dimensions.
  1. Hallucinations are defined as a perceptual experience that occurs in the absence of any external sensory input, and are most commonly auditory, but can occur in any modality.
  2. Delusions are distortions or exaggerations of inferential thinking, which lack any logical consistency, are not explained by cultural beliefs, and persist regardless of contradictory evidence. Persecutory delusions involve the belief that people are “out to get” the individual, resulting in a lack of trust in others. Delusion of reference refers to the belief that neutral events are directed specifically towards the individual. Somatic delusions involve the belief that the individual has a physical ailment contrary to medical advice. Delusions of grandeur are characterised by an exaggerated belief that the individual has power, ability, or fame. Positive symptoms can cause extreme distress for the person.
  • The ‘negative symptoms’ of schizophrenia refer to an absence of normal functions including a scarcity of facial expressions of emotion, reduced frequency and range of gestures and voice modulation, restricted eye contact, poverty of speech, reduced social interaction, reduced motivation, poor hygiene, and reduced experience of pleasure often manifesting as scarcity of recreation, inability to experience closeness, and reduced interest in any sexual activity. Deficit syndrome is a subtype of schizophrenia with persisting negative symptoms that is described by specifically defined assessments used primarily for research.
  • Disorganisation symptoms (Positive Formal Thought Disorder) include disorganised speech and behaviour, as well as inappropriate affect. Severely disorganised speech is difficult to follow, being incoherent, irrelevant and/or illogical. Disorganised speech may also be deprived of content, which is sometimes referred to as negative formal thought disorder symptoms. Disorganised behaviour includes bizarre or inappropriate behaviour, actions or gestures. Inappropriate (incongruous) affect involves exhibiting incorrect emotional responses for a given context. Symptoms of disorganisation have been identified as risk factors for poor illness outcome, and have a significant negative effect on a person’s day-to-day functioning and quality of life. There is evidence to suggest that disorganisation symptoms may be associated with impaired cognitive performance.

  • Movement disorders have been reported in people with schizophrenia, with tardive dyskinesia among the most commonly reported. This disorder is a ‘hyper-kinetic’ (excessive movement) disorder, characterised by jerky, involuntary movements, usually of the face and/or limbs. Parkinsonism is another movement disorder associated with schizophrenia, and is a ‘hypo-kinetic’ (reduced movement) disorder, characterised by slowness of movement and rigidity. Movement disorders are primarily associated with the use of antipsychotic medications, however they have also been reported in people who are antipsychotic-naïve.

  • Dermatoglyphics (epidermal ridges) are the distinct patterns and lines on the hands and fingers. These ridges appear on the hands between weeks 6 and 15 during foetal development, and remain largely unchanged after this period. 

  • Dissociation is described as disruption or discontinuity in the normal integration of consciousness, memory, identity, emotion, perception, body representation, motor control, or behaviour. Common dissociative experiences include mild forms of absorption, such as daydreaming. Less common and more severe dissociative experiences include amnesia, derealisation, depersonalisation, and fragmentation of identity.

  • Functional laterality refers to a natural asymmetry in left or right-side dominance, for example in terms of handedness, or brain function. 

  • Minor physical anomalies (MPAs) are subtle anatomical deviations that have little functional or aesthetic impact. They may be traced to events occurring prenatally and may represent risk markers for underlying illness susceptibility. MPAs may be important risk indicators when an individual is already at high risk of developing psychosis, for example, having a first-degree relative with psychosis, and when multiple MPAs occur together in one individual.

  • Morphometrics is the measurement of the variation in the structure or form of organisms. The study of body shapes and their prevalence in both physical and mental disorders may provide insight into the biology of and risk for schizophrenia.

  • Neurological soft signs (NSS) are neurological abnormalities that can be identified by clinical examination using valid and reliable testing measures (integrative sensory functioning, motor coordination, and complex motor sequencing).

  • Olfactory functioning: impaired odour detection, identification, and discrimination in people with schizophrenia compared to people without schizophrenia. 

  • Pain Sensitivity

  • Personality & Temperament

  • Sleep Disturbance: people with schizophrenia show large effects of shorter total sleep time, more awake time, longer sleep onset latency, and lower sleep efficiency. 

  • Temperature Regulation

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Special Populations & Their Influence on Schizophrenia
Special Populations & Their Influence on Schizophrenia
  • Children
  • Children of people with schizophrenia

  • Elderly

  • Ethnic Groups

  • Forensic Settings

  • Homeless People

  • Indigenous Populations

  • Migrants

  • Refugees

  • Sex Differences

  • Siblings

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Treatment For Schizophrenia
Treatment For Schizophrenia
  • Treatments during pregnancy and breastfeeding
  • Treatments for aggression and agitation

  • Treatments for childhood and early-onset schizophrenia

  • Treatments for cognitive symptoms

  • Treatment for Dual Diagnosis
  • Treatments for elderly people and people with late-onset schizophrenia

  • Treatments for first-episode psychosis

  • Treatments for high-risk groups

  • Treatments for medication non-adherence

  • Treatments for medication-resistant schizophrenia

  • Treatments for negative symptoms

  • Treatments for relapse prevention

  • Treatments for schizoaffective disorder

  • Antipsychotic combination treatment (antipsychotic polypharmacy) has been utilised in clinical practice for patients who are unresponsive or partially responsive to antipsychotic monotherapies.

  • Costs of Schizophrenia Treatment

  • Dosage of Schizophrenia Treatment

  • Mode of Administration

  • Placebo Response

  • Switching Medication

  • Alternative Treatments: possible replacement for antipsychotic medications, which can be associated with severe side effects. Alternative therapies may have less debilitating side effects, and so assessing their efficacy is important.

  • Anticonvulsants

  • Cannabidiol

  • Essential fatty acids

  • Glutamate receptor modulators

  • Herbal Medicines

  • Nicotine

  • Serotonin Modulators

  • Benzodiazepines

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Understanding Voices
Understanding Voices

Understanding Voices is a new website that will make it easier for people to find information about different approaches to voice-hearing and ways of supporting those who are struggling with the voices that they hear. It has been produced by Hearing the Voice (Durham University) in close collaboration with voice-hearers, their families and allies, and mental health professionals. The website covers a wide variety of topics, ranging from what it is like to hear voices and what’s happening in the brain, through to the pros and cons of medication, cognitive behavioural therapy and peer support. It will present practical techniques for managing distressing voices, information for families and friends, and also shed light on the links between voice-hearing and inner speech, trauma, creativity and spiritual or religious experience.

A History of Voice Hearing
A History of Voice Hearing

Experiences of hearing voices have played different roles for individuals and communities throughout human history in which voices have been interpreted, represented and understood within a European context. We look at the voices of medieval mystics, of people admitted to psychiatric asylums in the nineteenth century and of famous literary authors in the early twentieth century. We also look at the emergence from the late 1980s of the World Hearing Voices Movement – an international people’s movement.

  • Voices in medieval mysticism

  • Voices from the nineteenth-century asylum

  • Literary voices in the twentieth century

  • Millennial voices: An international people’s movement

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A History of Voice Hearing
A History of Voice Hearing

Experiences of hearing voices have played different roles for individuals and communities throughout human history in which voices have been interpreted, represented and understood within a European context. We look at the voices of medieval mystics, of people admitted to psychiatric asylums in the nineteenth century and of famous literary authors in the early twentieth century. We also look at the emergence from the late 1980s of the World Hearing Voices Movement – an international people’s movement.

  • Voices in medieval mysticism

  • Voices from the nineteenth-century asylum

  • Literary voices in the twentieth century

  • Millennial voices: An international people’s movement

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Coping Strategies to Deal With Hearing Voices
Coping Strategies to Deal With Hearing Voices

Coping strategies are practical techniques that can help us to manage day-to-day life. Voice Collective identify six different types of coping strategy:

  • Safety strategies: designed to help you feel calmer, safer and more secure. Useful if your voices threaten you, or make you feel scared or anxious.
  • Blocking strategies: can help you block out the voices or make them seem quieter and further away. Useful if you need a break from your experiences or want to concentrate on something else.
  • Empowering strategies: designed to change the power balance between you and the voices. Can help you feel more in control of your experiences.
  • Expressive strategies: useful when you want to express your feelings and the experiences you are going through. Can be carthartic and/or a way of letting off steam.
  • Compassionate strategies: can help you to be kinder to yourself when you’re distressed by your voices, emotions or other difficult experiences. May also involve being compassionate towards the voices themselves.
  • Connection strategies: helpful if you’re feeling isolated and alone, or disconnected from yourself, your body or the world in general

We all rely on coping strategies when dealing with difficult emotions, situations or relationships. Some people who get anxious using public transport might listen to music or audiobooks as a means of distraction. Others who are afraid of being in confined spaces might practice deep breathing or visualisation exercises to reduce the feeling of panic. This is a coping strategy toolkit which contains some ideas to get you started: 

  • Compassion
  • Being With Animals
  • Challenging the Voices
  • Filtering the Voices
  • Interrupting the Voices
  • Setting Boundaries with the Voices
  • Taking It One Step At A Time
  • Preparing In Advance
  • Identifying Patterns & Cycles
  • Connecting With Others
  • Creating Visualising
  • Grounding Objects
  • Praying
  • Creative Visualisation
  • Getting Out in Nature
  • Social Media
  • Getting Creative
  • Keeping Busy
  • Listening to Music
  • Listening to Podcasts or Audiobooks
  • Making Noise
  • TV or Gaming
  • Identifying Patterns or Cycles
  • Interpreting The Voices
  • Medication
  • Mindfulness
  • Walking
  • Soothing Pictures & Clips
  • Taking Care Of Yourself
  • Reminding Yourself of Your Strengths
  • Grounding Techniques

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Crisis Services
Crisis Services

Crisis services are for people feeling hopeless, suicidal or at risk of harm, immediate help and support.

  1. Emergency Services
  2. Listening Services
  3. Questions
  4. Coping in the Moment
  5. Crisis houses and services offer intensive, short-term support, usually in a community or residential setting, as opposed to a hospital setting. They can be run by NHS services, independent organisations or charities. Crisis houses or services might offer out of hours support or overnight stays.

Country
United Kingdom of Great Britain and Northern Ireland

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Exploring Voices
Exploring Voices

Exploring Voices explores different ways of understanding voices, including psychological, neuroscientific, historical, literary and spiritual approaches. They also present information and resources for young people who hear voices, and consider some of the factors that make voices likely to occur in older adults.

  • What is Hearing Voices?
  • Why Do People Experience Voices?
  • A History of Voices
  • Voices & Spirituality
  • Voices In Children & Adolescents
  • Voices in Older Adults

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Family & Friends of Voice Hearers
Family & Friends of Voice Hearers

Being the parent, family member or friend of someone who hears voices can be a complex experience – in turns bewildering, worrying and painful, but also, for some, an affirmation of their own strength and resilience. In this module, we explore the personal perspectives of people whose loved ones hear voices. We cover a range of different topics, including what you can do to support someone when they are distressed by their voices, and what you can do to seek support for yourself.

  • As a Parent, Family Member or Carer
  • As a Sibling
  • Carers Hub
  • As A Friend
  • As a child or adult child of a parent who hears voices

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Hearing Voices While At Work or Study
Hearing Voices While At Work or Study

Hearing voices can impact (both positively and negatively) on an individual’s ability to meet the demands of a job or to study at school or University. Working or studying can also influence the frequency with which voices occur and the content of what they say. In these pages, we explore different personal accounts of what it’s like to hear voices while working or studying, some strategies and techniques that people use to help them cope, and the rights and reasonable adjustments that voice-hearers may be entitled to from their employer or education provider.

  • Hearing Voices at Work
  • Hearing Voices While Studying
  • Rights & Reasonable Adjustments
  • Benefits & Financial Assistance

 

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Living With Voices
Living With Voices

Living With Voices covers a wide range of topics, including what to do in a crisis, coping strategies and how to open up conversations about voice-hearing, as well as ways to manage voices while working or studying. They also explore the links between voice-hearing and creativity, and provide practical information and advice for friends and family.

  • Coping With Voices
  • Talking About Voices
  • Hearing Voices at Work or While Studying
  • Voices & Creativity
  • For Friends & Family

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Medication For People Who Hear Voices
Medication For People Who Hear Voices

The Medication section of the Understanding Voices Website brings together reflections on personal experiences of taking medication, as well as information about its benefits and possible adverse effects. In an area that often involves controversy, conflicting information and strongly held views, we hope this part of our website encourages people to have the kind of conversations that support an informed choice.

  • What medications are used when people hear voices?

  • What is it like to take antipsychotics?

  • How might antipsychotics help with voices?

  • Adverse effects

  • Making an informed choice

  • Reducing or coming off medication

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Peer Support
Peer Support

Peer support is when people use their life experiences to help each other. There are many different forms of peer support, but they are all based on providing safe spaces where people can feel accepted and understood. In peer support, everyone’s views and experiences are equally valued and there is an emphasis on reciprocity and mutual aid – that is, people both give and receive support. Some practical examples of peer support in action include:

  • Out of hours crisis line
  • Peer support group
  • Activist collective
  • Peer support workers
  • Online forums
  • The Roots of Peer Support
  • The Values of Peer Support
  • The benefits and drawbacks of peer support
  • Hearing Voices Groups: peer support groups for people who hear voices, see visions or have other similar sensory experiences. They have their roots in the work of the Hearing Voices Movementicon (HVM),

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Talking About Voices
Talking About Voices

Talking About Voices is a section of our website is aimed at people considering having a conversation about voices with someone in their life, outside the context of mental health services. Here we explore personal reflections on talking about voices, some research around disclosure and stigma, and provide practical examples and suggestions for voice-hearers and those who support them.

  • Why can it be difficult to talk about voices?

  • Suggestions for voice-hearers

  • Suggestions for Supporters

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Therapies for People Who Hear Voices
Therapies for People Who Hear Voices

There are a number of therapeutic approaches used to treat people hearing voices. These include:

  • Cognitive approaches: talking therapies that focus on changing a person’s thoughts or beliefs about their voice-hearing experiences.
  • Talking with voices: approaches that involve engaging in a dialogue or conversation with voices. They typically focus on changing your relationship to the voice and ways of understanding or making sense of what the voices are saying.
  • Acceptance and Compassion: forms of talking therapy aimed at encouraging people to be kinder, more compassionate and more accepting of themselves, their voices and other people. This includes Compassion Focused Therapy (CFT) and Acceptance & Commitment Therapy (ACT)
  • Dealing with Trauma: therapies that are specifically designed to help people ‘work through’ or ‘process’ traumatic life experiences.
  • Emerging Therapies: tew approaches to the treatment of distressing voices that are currently being developed in the UK. Examples include Relating Therapy, Avatar Therapy, Neurostimulation and Open Dialogue.
  • Other therapies that people sometimes find helpful include family therapy, art therapy, drama and dance therapy and psychoanalytic approaches – follow the links in the text to learn more about these. 

You can find out more about each of these approaches by exploring the pages below. Other therapies that people sometimes find helpful include family therapy, art therapy, drama and dance therapy and psychoanalytic approaches – follow the links in the text to learn more about these. 

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Voices & Creativity
Voices & Creativity

Creative practices – such as producing art or writing poetry and fiction – can provide a way of communicating ideas and experiences which are very difficult to describe directly. Some voice-hearers find this particularly useful, not just because it allows them to communicate their experience to others, but also because it allows them to explore and reflect on their relationship with their voices. This website present a series of written interviews in which voice-hearing artists and writers explore and reflect on the links between voices and creativity. Thank you to those who contributed for sharing their ideas, thoughts and experiences so generously on this website.

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Voices & Spirituality
Voices & Spirituality

Voice-hearing is central to the histories and mythologies of the world’s spiritual and religious traditions. In many traditions, the sacred texts themselves are known as the ‘voice’ or ‘word’ of the divine. Today, many people understand their voices in spiritual or religious terms. This websites explore some key aspects of spiritual voices, and how spirituality can help people who find their voices distressing. We also look at the ways in which voices have been understood and represented in different religious and spiritual contexts, ranging from ‘hearing the voice of God’ in charismatic Christian communities and the role of voices in Shamanic traditions, through to contemporary cases of ‘mediumship’  – i.e. communication with the deceased.

  • Key themes in spiritual voices

  • Comfort & Revelation

  • Commands & Reform

  • Discernment, distress and the demonic

  • How Can Spirituality Help?

  • Hearing The Voice of God

  • Jinn in Contemporary Islam

  • Spiritualism and mediumship

  • Shamanism

  • Voices & Spiritual Crisis

  • Putting it into practice: Information and advice for clinicians

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Voices in Children & Adolescents
Voices in Children & Adolescents

Hearing voices in childhood or adolescence is quite common and not necessarily a cause for concern. For some young people, voice-hearing is a normal part of everyday life – a source of amusement, company or support. For others, it can be distressing and hard to manage, causing difficulties at school or college, problems with mental health, and disruption to their relationships with family and friends. The website consider a range of issues related to voice-hearing in children and young people. We include links to personal accounts and the latest academic research, as well as information about where you can find support if you’re a young person struggling to cope with the voices you hear, or the parent or supporter of someone in this situation.

  • Voices & Imaginary Friends
  • Young people and hearing voices

  • Resources for young people, parents and other supporters

  • Voice Collective

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Voices in Older Adults
Voices in Older Adults

s people get older, it is not uncommon to start to hear or see things that other people do not. Hearing a voice call your name or seeing a person who cannot be there are experiences that can occur throughout life, but certain things seem to make them likely to happen in older adults. Here we review some of these factors, including sensory loss, changes to the brain, loneliness and bereavement, among others. We also provide information about sources of support for older adults who hear voices and those who care for or about them. It’s important to note at the outset that while there is quite of a lot of research into visions and feelings of presence in older adults, there is relatively little that specifically focuses on experiences of hearing voices. In what follows, we discuss a range of different experiences, drawing attention to research that is directly related to voice-hearing where it is available.

  • Sensory Loss
  • Changes in the brain

  • Bereavement

  • Loneliness

  • Physical illness and other causes

  • Support For Older People

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What is Hearing Voices?
What is Hearing Voices?

Hearing voices refers to the experience of hearing a voice that no one else can hear. It describes experiences like the above which are very real to the person, do not feel within their control, and are not shared by anyone else.

  • What is it like to hear voices?
  • How common is hearing voices?

  • Hearing voices and psychiatric diagnosis

  • Finding meaning in voices

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Why Do People Hear Voices
Why Do People Hear Voices
  • Voices & Inner Speech
  • Voices & Trauma
  • Voices & Adversity
  • Voices & The Brain
  • Finding Meaning In Voices

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Working With Voices
Working With Voices

Working With Voices highlights the different ways to get help with voices, and things mental health professionals can do to support people who are struggling with the voices that they hear.

  • Medication
  • Therapy
  • Peer Support

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Who's Crazy Now
Who's Crazy Now

Who's Crazy Now is a website promoting Elly Litvak mental health services. Based in Toronto Canada, Elly Litvak is a wellness and recovery specialist with over 25 years’ experience in mental health.  Elly has established a variety of recovery-oriented programs within the Canadian mental health system and deliver workshops to mental health professionals, families, and people with the lived experience. As a trained actor and comedian, Elly Litvak is an ardent believer in healing through creativity, the arts and performance. 

 

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Country: Canada

Email: elly@ellylitvak.com

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